C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 4, p107/p130-binding
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000205250 E2F4 9606 + 16:67192169-67198918 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379378 E2F4-001 67192169-67198918 protein_coding
  ENST00000561904 E2F4-013 67192215-67194918 retained_intron
  ENST00000563238 E2F4-007 67192213-67193484 retained_intron
  ENST00000564718 E2F4-011 67192495-67194825 processed_transcript
  ENST00000565226 E2F4-005 67194952-67198229 protein_coding
  ENST00000565849 E2F4-010 67192190-67194819 nonsense_mediated_decay
  ENST00000566368 E2F4-012 67192527-67193060 retained_intron
  ENST00000567007 E2F4-002 67192185-67198917 retained_intron
  ENST00000567228 E2F4-004 67195651-67198219 retained_intron
  ENST00000568485 E2F4-009 67192174-67193278 retained_intron
  ENST00000568693 E2F4-003 67193978-67194799 retained_intron
  ENST00000568839 E2F4-006 67192207-67196008 nonsense_mediated_decay
  ENST00000569573 E2F4-008 67192208-67196008 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379378ENST00000561904ENST00000563238ENST00000564718ENST00000565849ENST00000567007
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379378 16.930±0.00 32.809±0.00 0.839±0.00 4.178±1.70 9.076±5.79 8.491±4.48 7.383±6.31 12.098±8.86 5.200±0.44 9.908±8.62 10.316±7.63 24.515±14.12 37.755±9.34 20.631±2.61
ENST00000561904 N/A N/A N/A N/A N/A N/A 0.550±0.00 N/A N/A 1.288±0.00 N/A 2.312±0.00 N/A 11.992±0.00
ENST00000563238 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.249±0.00 14.455±0.00
ENST00000564718 N/A N/A 1.356±0.00 N/A N/A 2.043±0.00 N/A N/A N/A 1.153±0.00 N/A 14.347±0.00 17.431±0.00 N/A
ENST00000565849 N/A N/A N/A N/A 3.390±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000567007 N/A N/A N/A 1.004±0.41 N/A N/A N/A N/A N/A 0.360±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WN CIL_0007WN_0001 VISTA 16:66603173-67205657
CIL_0005SV CIL_0005SV_0001 CGP 16:67184366-67198918
CIL_0003M2 CIL_0003M2_0002 CGP 16:67192169-67204029

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000083 IEA regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0002064 IEA epithelial cell development
GO:0003677 IMP DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006884 IEA cell volume homeostasis
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008015 IEA blood circulation
GO:0008134 IPI transcription factor binding
GO:0008361 IEA regulation of cell size
GO:0009887 IEA organ morphogenesis
GO:0010467 TAS gene expression
GO:0019904 IPI protein domain specific binding
GO:0042127 IEA regulation of cell proliferation
GO:0042384 IEA cilium assembly
GO:0044458 ISS motile cilium assembly
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0098534 ISS centriole assembly
GO:1903251 ISS multi-ciliated epithelial cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029358 e2f4 E2F transcription factor 4 protein_coding Danio_rerio
ENSMUSG00000014859 E2f4 E2F transcription factor 4 protein_coding Mus_musculus

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