C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014859 E2f4 10090 + 8:105297663-105305369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015003 E2f4-201 105297663-105305369 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015003
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015003 37.865±6.82 39.922±2.63 26.188±5.12 29.076±10.69 43.292±15.25 46.174±6.67 18.215±2.69 30.901±2.17 96.411±92.55 43.727±1.71 12.939±1.04 53.914±19.98 41.278±6.85 14.825±6.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005SV CIL_0005SV_0002 CGP 8:105289924-105305369
CIL_0003M2 CIL_0003M2_0003 CGP 8:105297663-105310623

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000083 IDA regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0002064 IMP epithelial cell development
GO:0003677 IDA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 TAS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006884 IMP cell volume homeostasis
GO:0008015 IMP blood circulation
GO:0008134 IEA transcription factor binding
GO:0008361 IMP regulation of cell size
GO:0009887 IMP organ morphogenesis
GO:0019904 IEA protein domain specific binding
GO:0042127 IDA regulation of cell proliferation
GO:0042384 IMP cilium assembly
GO:0044458 ISS motile cilium assembly
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051726 TAS regulation of cell cycle
GO:0098534 ISS centriole assembly
GO:1903251 ISS multi-ciliated epithelial cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029358 e2f4 E2F transcription factor 4 protein_coding Danio_rerio
ENSG00000205250 E2F4 E2F transcription factor 4, p107/p130-binding protein_coding Homo_sapiens

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