C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: conserved helix-loop-helix ubiquitous kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213341 CHUK 9606 - 10:100188298-100229619 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370397 CHUK-001 100188298-100229619 protein_coding
  ENST00000585551 CHUK-004 100190671-100193423 processed_transcript
  ENST00000588656 CHUK-003 100189192-100194079 processed_transcript
  ENST00000590930 CHUK-002 100188367-100195942 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000370397
Transcript ID Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000370397 1.933±0.00 1.419±0.00 3.201±0.30 2.393±0.00 3.072±0.00 3.828±0.42 2.375±0.00 1.758±0.45 1.545±1.12 4.919±1.35 3.023±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005DZ CIL_0005DZ_0001 CGP 10:100150094-100229619
CIL_0007QB CIL_0007QB_0001 VISTA 10:100185085-100786577
CIL_0005DW CIL_0005DW_0001 CGP 10:100188298-100267680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001101 IEA response to acid
GO:0002011 IEA morphogenesis of an epithelial sheet
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003009 IEA skeletal muscle contraction
GO:0004672 IDA:IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0006954 TAS inflammatory response
GO:0006955 TAS immune response
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007249 TAS I-kappaB kinase/NF-kappaB signaling
GO:0007252 TAS I-kappaB phosphorylation
GO:0007266 IEA Rho protein signal transduction
GO:0007595 IEA lactation
GO:0008384 TAS:IEA IkappaB kinase activity
GO:0008385 TAS IkappaB kinase complex
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009615 TAS response to virus
GO:0009636 IEA response to toxic substance
GO:0009653 TAS anatomical structure morphogenesis
GO:0009898 ISS cytoplasmic side of plasma membrane
GO:0010033 IEA response to organic substance
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030316 IEA osteoclast differentiation
GO:0032481 TAS positive regulation of type I interferon production
GO:0032496 IEA response to lipopolysaccharide
GO:0033194 IEA response to hydroperoxide
GO:0033598 IEA mammary gland epithelial cell proliferation
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035631 ISS CD40 receptor complex
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042493 IEA response to drug
GO:0042803 IDA protein homodimerization activity
GO:0043123 TAS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043200 IEA response to amino acid
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045087 TAS innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0051146 IEA striated muscle cell differentiation
GO:0060749 IEA mammary gland alveolus development
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway
GO:0071356 IDA cellular response to tumor necrosis factor
GO:0097110 IDA scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011662 chuk conserved helix-loop-helix ubiquitous kinase protein_coding Danio_rerio
ENSMUSG00000025199 Chuk conserved helix-loop-helix ubiquitous kinase protein_coding Mus_musculus

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