C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: conserved helix-loop-helix ubiquitous kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025199 Chuk 10090 - 19:44073335-44107480 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026217 Chuk-001 44073335-44107480 protein_coding
  ENSMUST00000119591 Chuk-002 44073336-44107477 protein_coding
  ENSMUST00000123806 Chuk-007 44076938-44079035 retained_intron
  ENSMUST00000134495 Chuk-005 44077245-44084450 retained_intron
  ENSMUST00000144286 Chuk-006 44078290-44079282 retained_intron
  ENSMUST00000146861 Chuk-004 44097197-44107282 retained_intron
  ENSMUST00000147423 Chuk-003 44081415-44107469 retained_intron
  ENSMUST00000149091 Chuk-008 44074373-44075904 retained_intron

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026217ENSMUST00000119591ENSMUST00000144286ENSMUST00000147423
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026217 6.028±0.96 17.235±3.31 5.896±1.30 18.717±0.69 5.143±1.61 9.254±0.97 3.188±0.73 14.974±1.46 12.070±3.71 4.923±1.10 1.599±0.48 6.877±1.54 12.564±5.75 3.484±0.75
ENSMUST00000119591 N/A N/A 2.889±0.00 N/A 1.894±0.49 2.326±0.55 1.343±0.10 5.207±0.81 6.960±3.21 3.801±0.00 0.860±0.17 2.464±0.97 5.176±0.70 1.313±0.41
ENSMUST00000144286 N/A N/A N/A 22.465±0.00 N/A N/A N/A N/A N/A N/A N/A 23.271±0.00 N/A N/A
ENSMUST00000147423 N/A 23.241±4.22 N/A 4.975±1.94 4.707±0.00 3.884±1.01 N/A N/A N/A 2.806±0.00 N/A 5.097±1.98 N/A 1.875±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005DZ CIL_0005DZ_0002 CGP 19:44034944-44107480
CIL_0005DW CIL_0005DW_0002 CGP 19:44073335-44135876

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001101 IEA response to acid
GO:0002011 IMP morphogenesis of an epithelial sheet
GO:0003009 IEA skeletal muscle contraction
GO:0004672 IDA protein kinase activity
GO:0004702 TAS receptor signaling protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 IEA cytosol
GO:0007252 TAS I-kappaB phosphorylation
GO:0007266 IEA Rho protein signal transduction
GO:0007595 IGI lactation
GO:0008384 IEA IkappaB kinase activity
GO:0008385 IEA IkappaB kinase complex
GO:0009636 IEA response to toxic substance
GO:0010033 IEA response to organic substance
GO:0023014 TAS signal transduction by phosphorylation
GO:0030316 IGI osteoclast differentiation
GO:0032496 IEA response to lipopolysaccharide
GO:0033194 IEA response to hydroperoxide
GO:0033598 IGI mammary gland epithelial cell proliferation
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043200 IEA response to amino acid
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0051146 IEA striated muscle cell differentiation
GO:0060749 IGI mammary gland alveolus development
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0097110 ISO scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011662 chuk conserved helix-loop-helix ubiquitous kinase protein_coding Danio_rerio
ENSG00000213341 CHUK conserved helix-loop-helix ubiquitous kinase protein_coding Homo_sapiens

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