C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sphingosine-1-phosphate receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213694 S1PR3 9606 + 9:88991447-89005010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358157 S1PR3-002 88991447-89005010 protein_coding
  ENST00000375846 S1PR3-001 88996506-89005010 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358157ENST00000375846
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358157 6.920±0.00 16.754±0.00 1.873±0.00 2.698±2.38 1.996±0.40 4.870±3.75 6.426±5.71 11.878±11.27 2.004±0.05 3.014±2.58 2.100±0.00 3.085±1.71 8.637±1.34 3.583±3.09
ENST00000375846 N/A N/A N/A 0.048±0.00 0.114±0.00 N/A N/A 0.074±0.00 0.190±0.00 N/A 0.109±0.00 N/A N/A 0.073±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000077 CIL_000077_0002 CGP 9:88991447-89178767

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IEA cytokine production
GO:0003376 IEA sphingosine-1-phosphate signaling pathway
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005178 IPI integrin binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006954 IEA inflammatory response
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0008284 TAS positive regulation of cell proliferation
GO:0008289 TAS lipid binding
GO:0009653 TAS anatomical structure morphogenesis
GO:0016021 IEA integral component of membrane
GO:0032651 IEA regulation of interleukin-1 beta production
GO:0038036 IEA sphingosine-1-phosphate receptor activity
GO:1903141 IMP negative regulation of establishment of endothelial barrier

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087622 FP085391.2 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000067586 S1pr3 sphingosine-1-phosphate receptor 3 protein_coding Mus_musculus

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