C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingosine-1-phosphate receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375846 S1PR3-001 ENSG00000213694 9606 + 9:88996506-89005010 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastKidneyLiverMuscleTestisENST00000375846
Transcript ID Brain Breast Kidney Liver Muscle Testis
ENST00000375846 0.048±0.00 0.114±0.00 0.074±0.00 0.190±0.00 0.109±0.00 0.073±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000077 CIL_000077_0002 CGP 9:88991447-89178767

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001816 IEA cytokine production
GO:0003376 IEA sphingosine-1-phosphate signaling pathway
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005178 IPI integrin binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006954 IEA inflammatory response
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0008284 TAS positive regulation of cell proliferation
GO:0008289 TAS lipid binding
GO:0009653 TAS anatomical structure morphogenesis
GO:0016021 IEA integral component of membrane
GO:0032651 IEA regulation of interleukin-1 beta production
GO:0038036 IEA sphingosine-1-phosphate receptor activity
GO:1903141 IMP negative regulation of establishment of endothelial barrier

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087978 S1pr3-201 protein_coding Mus_musculus 0 1203
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.00004 57

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