C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: killer cell lectin-like receptor subfamily K, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213809 KLRK1 9606 - 12:10372353-10391874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000240618 KLRK1-001 10372353-10390018 protein_coding
  ENST00000396451 KLRK1-002 10373185-10391874 nonsense_mediated_decay
  ENST00000540267 KLRK1-004 10372416-10382182 retained_intron
  ENST00000540818 KLRK1-005 10372980-10388976 protein_coding
  ENST00000544449 KLRK1-003 10372807-10390025 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000240618ENST00000396451ENST00000540267ENST00000544449
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000240618 N/A 6.412±0.00 0.055±0.00 0.860±0.35 0.680±0.39 0.200±0.00 2.061±0.00 0.252±0.00 3.200±0.17 0.041±0.00 1.150±0.37 0.746±0.40 1.276±0.04
ENST00000396451 N/A N/A N/A N/A 2.203±0.00 N/A N/A 2.014±0.00 N/A N/A N/A N/A N/A
ENST00000540267 N/A N/A N/A N/A N/A N/A N/A 0.117±0.00 N/A N/A N/A N/A 1.380±0.00
ENST00000544449 0.086±0.00 1.325±0.00 0.113±0.00 0.316±0.00 N/A 0.094±0.00 N/A N/A 0.949±0.00 0.094±0.08 0.380±0.00 0.067±0.00 0.935±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00054H CIL_00054H_0001 CGP 12:10226058-10410146
CIL_0000T5 CIL_0000T5_0001 CGP 12:10372353-10409757

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0009986 IDA cell surface
GO:0016021 TAS integral component of membrane
GO:0030101 TAS natural killer cell activation
GO:0030154 IEA cell differentiation
GO:0030246 IEA carbohydrate binding
GO:0031295 TAS T cell costimulation
GO:0045087 TAS innate immune response
GO:0045954 IDA positive regulation of natural killer cell mediated cytotoxicity
GO:0050776 TAS regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000030149 Klrk1 killer cell lectin-like receptor subfamily K, member 1 protein_coding Mus_musculus

Loading