C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ALG3, alpha-1,3- mannosyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000214160 ALG3 9606 - 3:184242301-184249548 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000397676 ALG3-001 184242334-184248971 protein_coding
  ENST00000411922 ALG3-004 184242301-184248962 nonsense_mediated_decay
  ENST00000414845 ALG3-013 184242885-184248933 nonsense_mediated_decay
  ENST00000423996 ALG3-007 184243791-184248949 nonsense_mediated_decay
  ENST00000445626 ALG3-002 184242425-184249548 protein_coding
  ENST00000446569 ALG3-014 184242574-184248935 protein_coding
  ENST00000455059 ALG3-003 184242469-184249520 protein_coding
  ENST00000461415 ALG3-006 184244759-184248950 retained_intron
  ENST00000462735 ALG3-010 184243554-184245021 retained_intron
  ENST00000463495 ALG3-011 184242961-184243996 processed_transcript
  ENST00000477959 ALG3-009 184244329-184245342 retained_intron
  ENST00000482048 ALG3-008 184245067-184248929 retained_intron
  ENST00000485912 ALG3-012 184242459-184243589 retained_intron
  ENST00000488976 ALG3-005 184244778-184248962 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397676ENST00000411922ENST00000414845ENST00000423996ENST00000445626ENST00000446569ENST00000455059ENST00000461415ENST00000463495ENST00000477959ENST00000482048ENST00000485912ENST00000488976
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397676 3.644±0.00 9.821±0.00 N/A 2.118±0.71 6.587±0.00 4.358±3.65 1.493±0.00 7.118±0.00 14.340±0.00 2.611±1.28 3.213±0.00 12.478±7.61 21.850±13.77 11.349±2.38
ENST00000411922 N/A N/A 1.215±0.00 N/A 0.338±0.00 N/A 0.129±0.00 N/A N/A N/A 2.734±0.00 N/A N/A N/A
ENST00000414845 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.757±0.00 N/A N/A
ENST00000423996 9.742±0.00 8.601±0.00 N/A N/A 8.223±0.00 5.458±0.00 0.131±0.00 N/A N/A N/A N/A 27.166±0.00 16.000±0.00 12.050±0.00
ENST00000445626 N/A N/A N/A N/A N/A 0.357±0.00 N/A N/A N/A 0.552±0.00 0.900±0.00 5.996±4.80 3.083±0.00 N/A
ENST00000446569 4.203±0.00 N/A N/A N/A 5.146±0.00 2.531±1.16 1.169±0.80 N/A 1.114±0.00 N/A 5.589±0.00 N/A 8.051±0.00 8.605±0.00
ENST00000455059 N/A N/A N/A N/A N/A N/A N/A N/A 0.591±0.00 N/A N/A 0.670±0.00 N/A N/A
ENST00000461415 N/A N/A N/A N/A 0.723±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000463495 N/A N/A 6.007±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000477959 N/A N/A N/A N/A 0.912±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000482048 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.818±0.00 N/A N/A
ENST00000485912 N/A 2.930±0.00 0.930±0.00 N/A 0.959±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000488976 N/A N/A N/A N/A N/A N/A N/A N/A 0.582±0.00 1.227±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758
CIL_0005FP CIL_0005FP_0001 CGP 3:184186023-184242329
CIL_0005FO CIL_0005FO_0001 CGP 3:184230429-184249548
CIL_000573 CIL_000573_0001 CGP 3:184242301-184293031

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000033 IDA alpha-1,3-mannosyltransferase activity
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006486 NAS protein glycosylation
GO:0006488 TAS dolichol-linked oligosaccharide biosynthetic process
GO:0008152 IEA metabolic process
GO:0016021 IEA integral component of membrane
GO:0016758 IEA transferase activity, transferring hexosyl groups
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0052925 IEA dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
GO:0097502 IEA mannosylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053155 alg3 asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) protein_coding Danio_rerio
ENSMUSG00000033809 Alg3 asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase) protein_coding Mus_musculus

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