C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 17-like family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000223443 USP17L2 9606 - 8:12137168-12139077 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333796 USP17L2-001 12137168-12139077 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonLiverLungOvaryPlacentaTestisENST00000333796
Transcript ID Brain Breast Colon Liver Lung Ovary Placenta Testis
ENST00000333796 0.121±0.00 0.213±0.00 0.044±0.00 0.247±0.00 0.120±0.00 0.025±0.00 0.030±0.00 0.008±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PQ CIL_0007PQ_0001 VISTA 8:11649159-12249913
CIL_0001XF CIL_0001XF_0002 CGP 8:12132417-12139077

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000075 IMP cell cycle checkpoint
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IMP ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006915 IEA apoptotic process
GO:0007093 IMP mitotic cell cycle checkpoint
GO:0010955 IMP negative regulation of protein processing
GO:0016579 IDA protein deubiquitination
GO:0030334 IMP regulation of cell migration
GO:0031064 IMP negative regulation of histone deacetylation
GO:0032321 IMP positive regulation of Rho GTPase activity
GO:0034261 IDA negative regulation of Ras GTPase activity
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042127 IMP regulation of cell proliferation
GO:0042981 IMP regulation of apoptotic process
GO:0050691 IMP regulation of defense response to virus by host
GO:0070536 IMP protein K63-linked deubiquitination
GO:0071108 IMP protein K48-linked deubiquitination
GO:0071586 IMP CAAX-box protein processing
GO:0090315 IMP negative regulation of protein targeting to membrane
GO:1900027 IMP regulation of ruffle assembly
GO:1900245 IMP positive regulation of MDA-5 signaling pathway
GO:1900246 IMP positive regulation of RIG-I signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077300 usp42 ubiquitin specific peptidase 42 protein_coding Danio_rerio
ENSMUSG00000043073 Usp17le ubiquitin specific peptidase 17-like E protein_coding Mus_musculus
ENSMUSG00000054568 Usp17la ubiquitin specific peptidase 17-like A protein_coding Mus_musculus
ENSMUSG00000057321 Usp17ld ubiquitin specific peptidase 17-like D protein_coding Mus_musculus
ENSMUSG00000058976 Usp17lc ubiquitin specific peptidase 17-like C protein_coding Mus_musculus
ENSMUSG00000062369 Usp17lb ubiquitin specific peptidase 17-like B protein_coding Mus_musculus

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