C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DO beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000241106 HLA-DOB 9606 - 6:32812763-32817048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000438763 HLA-DOB-001 32812763-32817048 protein_coding
  ENST00000447394 HLA-DOB-004 32814370-32816910 protein_coding
  ENST00000475235 HLA-DOB-002 32813047-32816988 retained_intron
  ENST00000488325 HLA-DOB-003 32812763-32816976 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalENST00000438763
Transcript ID Adrenal
ENST00000438763 22.128±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PK CIL_0001PK_0003 CGP 6:32756098-32817048

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002587 IDA negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005764 IDA lysosome
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0032395 TAS MHC class II receptor activity
GO:0042613 IDA:IEA MHC class II protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000053738 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSDARG00000054921 wu:fd58b11 wu:fd58b11 protein_coding Danio_rerio
ENSDARG00000055447 si:busm1-194e12.12 si:busm1-194e12.12 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb major histocompatibility complex class II DBB gene protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab major histocompatibility complex class II DAB gene protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 si:busm1-228j01.4 protein_coding Danio_rerio
ENSDARG00000093706 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSMUSG00000041538 H2-Ob histocompatibility 2, O region beta locus protein_coding Mus_musculus

Loading