C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histocompatibility 2, O region beta locus
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041538 H2-Ob 10090 + 17:34238903-34245907 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000095342 H2-Ob-001 34238903-34245907 protein_coding
  ENSMUST00000167280 H2-Ob-003 34238931-34245798 protein_coding
  ENSMUST00000173681 H2-Ob-004 34238905-34241504 retained_intron
  ENSMUST00000173764 H2-Ob-002 34240036-34244460 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000095342ENSMUST00000167280ENSMUST00000173681ENSMUST00000173764
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000095342 0.815±0.44 0.331±0.14 0.354±0.09 0.102±0.09 17.059±11.02 0.636±0.14 0.791±0.69 0.773±0.44 0.310±0.20 5.200±0.89 1.016±1.35 0.766±0.30 0.046±0.03 0.023±0.01
ENSMUST00000167280 N/A N/A N/A 0.018±0.01 N/A N/A N/A N/A 0.048±0.00 N/A 0.039±0.01 N/A 0.018±0.01 0.024±0.00
ENSMUST00000173681 N/A 0.251±0.00 N/A 1.186±0.00 N/A N/A N/A N/A 0.164±0.00 N/A 0.088±0.02 1.642±0.00 N/A 0.198±0.00
ENSMUST00000173764 0.236±0.00 0.326±0.00 N/A N/A 10.330±0.00 1.615±0.40 N/A 0.908±0.68 0.367±0.24 N/A 0.071±0.05 0.893±0.38 0.049±0.02 0.052±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PK CIL_0001PK_0006 CGP 17:34238903-34269418

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0002587 IEA negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0005622 IDA intracellular
GO:0005764 IEA lysosome
GO:0006955 IEA immune response
GO:0016021 IEA integral component of membrane
GO:0023026 IEA MHC class II protein complex binding
GO:0042613 IEA MHC class II protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000053738 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSDARG00000054921 wu:fd58b11 wu:fd58b11 protein_coding Danio_rerio
ENSDARG00000055447 si:busm1-194e12.12 si:busm1-194e12.12 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb major histocompatibility complex class II DBB gene protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab major histocompatibility complex class II DAB gene protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 si:busm1-228j01.4 protein_coding Danio_rerio
ENSDARG00000093706 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSG00000241106 HLA-DOB major histocompatibility complex, class II, DO beta protein_coding Homo_sapiens

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