C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GTPase activating protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000241484 ARHGAP8 9606 + 22:44752558-44862788 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336963 ARHGAP8-003 44752603-44862788 protein_coding
  ENST00000356099 ARHGAP8-004 44752606-44862784 protein_coding
  ENST00000389772 ARHGAP8-005 44786457-44862784 nonsense_mediated_decay
  ENST00000389774 ARHGAP8-001 44752558-44862784 protein_coding
  ENST00000396119 ARHGAP8-012 44752586-44809098 protein_coding
  ENST00000412433 ARHGAP8-010 44752705-44814718 protein_coding
  ENST00000447333 ARHGAP8-013 44752586-44825591 nonsense_mediated_decay
  ENST00000460809 ARHGAP8-002 44752574-44850963 retained_intron
  ENST00000469342 ARHGAP8-016 44859661-44862463 retained_intron
  ENST00000469872 ARHGAP8-011 44765229-44786508 processed_transcript
  ENST00000495219 ARHGAP8-017 44786552-44808809 retained_intron
  ENST00000498310 ARHGAP8-014 44801820-44825551 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000356099ENST00000389772ENST00000389774ENST00000412433ENST00000447333ENST00000460809ENST00000498310
Transcript ID Bladder Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000356099 3.046±0.00 N/A 1.453±0.00 N/A N/A N/A 1.103±0.00 4.762±2.60 10.918±1.46 N/A
ENST00000389772 N/A N/A N/A N/A N/A 0.411±0.00 0.482±0.00 13.512±0.00 N/A 2.334±0.00
ENST00000389774 N/A N/A N/A N/A 7.090±0.00 N/A N/A N/A N/A 3.197±0.00
ENST00000412433 N/A N/A N/A 0.271±0.00 N/A N/A N/A N/A N/A N/A
ENST00000447333 N/A 0.423±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000460809 0.874±0.00 0.198±0.00 1.108±0.00 0.084±0.00 N/A N/A N/A 2.158±1.18 N/A 0.771±0.00
ENST00000498310 N/A N/A N/A N/A N/A N/A N/A 3.712±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003JU CIL_0003JU_0001 CGP 22:44668547-44862784
CIL_00054G CIL_00054G_0001 CGP 22:44752558-45009999

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000078954 Arhgap8 Rho GTPase activating protein 8 protein_coding Mus_musculus

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