C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NFS1 cysteine desulfurase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000244005 NFS1 9606 - 20:35668055-35699359 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306750 NFS1-006 35694572-35699304 protein_coding
  ENST00000374085 NFS1-003 35668699-35699189 protein_coding
  ENST00000374092 NFS1-001 35668055-35699359 protein_coding
  ENST00000397425 NFS1-009 35668983-35699349 protein_coding
  ENST00000413203 NFS1-011 35681965-35699352 nonsense_mediated_decay
  ENST00000419569 NFS1-013 35690471-35699189 protein_coding
  ENST00000421540 NFS1-010 35690526-35699355 processed_transcript
  ENST00000440385 NFS1-002 35668993-35699355 nonsense_mediated_decay
  ENST00000456462 NFS1-012 35690413-35699352 nonsense_mediated_decay
  ENST00000471137 NFS1-008 35673758-35674798 retained_intron
  ENST00000480655 NFS1-004 35668964-35676186 retained_intron
  ENST00000489163 NFS1-007 35674531-35682791 processed_transcript
  ENST00000498084 NFS1-005 35668964-35674066 processed_transcript
  ENST00000541387 NFS1-017 35669471-35699352 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleTestisENST00000397425
Transcript ID Brain Heart Kidney Liver Muscle Testis
ENST00000397425 18.979±0.00 16.597±0.00 30.105±0.00 11.892±0.00 10.519±0.00 22.704±1.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AA CIL_0006AA_0001 CGP 20:35648925-35699359
CIL_000135 CIL_000135_0001 CGP 20:35668055-35700984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005759 IDA mitochondrial matrix
GO:0005829 IDA cytosol
GO:0006461 TAS protein complex assembly
GO:0006520 IEA cellular amino acid metabolic process
GO:0006534 IEA cysteine metabolic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006777 IEA Mo-molybdopterin cofactor biosynthetic process
GO:0008152 IEA metabolic process
GO:0016829 IEA lyase activity
GO:0018283 IDA iron incorporation into metallo-sulfur cluster
GO:0030170 IEA pyridoxal phosphate binding
GO:0031071 IDA:IEA cysteine desulfurase activity
GO:0032324 TAS molybdopterin cofactor biosynthetic process
GO:0042803 IDA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062237 nfs1 NFS1 nitrogen fixation 1 (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000027618 Nfs1 nitrogen fixation gene 1 (S. cerevisiae) protein_coding Mus_musculus

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