C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hemoglobin, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000244734 HBB 9606 - 11:5225464-5229395 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335295 HBB-001 5225464-5227071 protein_coding
  ENST00000380315 HBB-004 5226620-5229395 protein_coding
  ENST00000475226 HBB-003 5225655-5226823 retained_intron
  ENST00000485743 HBB-002 5226263-5227072 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335295ENST00000475226
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335295 294.971±0.00 147.631±0.00 13.131±0.00 45.882±37.96 404.777±340.62 1242.421±1233.12 38.336±23.43 6.851±0.93 57.562±35.70 7271.688±7182.31 15.480±4.74 85.572±85.84 7052.311±4836.11 373.865±323.34
ENST00000475226 265.573±0.00 132.892±0.00 N/A 75.495±0.00 706.439±0.00 2112.020±0.00 17.648±0.00 4.187±0.00 N/A 4785.690±0.00 N/A N/A N/A 615.688±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PR CIL_0007PR_0001 VISTA 11:4975331-5576811
CIL_0003R8 CIL_0003R8_0004 CGP 11:5225464-5235370

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004601 IDA peroxidase activity
GO:0005344 IEA:NAS oxygen transporter activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005829 TAS cytosol
GO:0005833 IEA:NAS hemoglobin complex
GO:0007596 TAS blood coagulation
GO:0008217 IEA regulation of blood pressure
GO:0010942 IDA positive regulation of cell death
GO:0015671 IEA:NAS oxygen transport
GO:0015701 TAS bicarbonate transport
GO:0019825 IEA:IDA oxygen binding
GO:0020037 IEA heme binding
GO:0030185 NAS nitric oxide transport
GO:0030492 IDA hemoglobin binding
GO:0031720 IDA haptoglobin binding
GO:0031838 IDA haptoglobin-hemoglobin complex
GO:0042542 IDA response to hydrogen peroxide
GO:0042744 IDA hydrogen peroxide catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045429 NAS positive regulation of nitric oxide biosynthetic process
GO:0050880 IEA regulation of blood vessel size
GO:0051291 IDA protein heterooligomerization
GO:0055114 IDA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0070293 IMP renal absorption
GO:0070527 IMP platelet aggregation
GO:0071682 TAS endocytic vesicle lumen
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038147 hbbe3 hemoglobin beta embryonic-3 protein_coding Danio_rerio
ENSDARG00000045143 hbbe2 hemoglobin beta embryonic-2 protein_coding Danio_rerio
ENSDARG00000069734 zgc:92880 zgc:92880 protein_coding Danio_rerio
ENSDARG00000087390 si:ch211-5k11.12 si:ch211-5k11.12 protein_coding Danio_rerio
ENSDARG00000089087 ba1 ba1 globin protein_coding Danio_rerio
ENSDARG00000089963 hbbe1.1 hemoglobin beta embryonic-1.1 protein_coding Danio_rerio
ENSDARG00000090689 hbbe1.2 hemoglobin beta embryonic-1.2 protein_coding Danio_rerio
ENSDARG00000097238 ba1l ba1 globin, like protein_coding Danio_rerio
ENSMUSG00000052305 Hbb-bs hemoglobin, beta adult s chain protein_coding Mus_musculus
ENSMUSG00000073940 Hbb-bt hemoglobin, beta adult t chain protein_coding Mus_musculus

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