C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: farnesyltransferase, CAAX box, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000257365 FNTB 9606 + 14:64986720-65062652 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246166 FNTB-001 64986720-65062598 protein_coding
  ENST00000554210 FNTB-004 65012172-65032392 retained_intron
  ENST00000554334 FNTB-002 65015538-65062652 retained_intron
  ENST00000555372 FNTB-006 64986895-65022130 processed_transcript
  ENST00000555618 FNTB-007 65027387-65027781 retained_intron
  ENST00000555742 FNTB-003 64987215-65027599 processed_transcript
  ENST00000556709 FNTB-005 65016504-65040827 processed_transcript
  ENST00000557300 FNTB-008 65053160-65061405 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENST00000246166
Transcript ID Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENST00000246166 1.421±0.00 7.058±0.00 7.344±0.00 2.508±0.00 4.173±0.00 3.794±0.00 7.109±2.21 6.335±2.01 9.167±1.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001K4 CIL_0001K4_0002 CGP 14:64986720-65102695

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004311 IEA farnesyltranstransferase activity
GO:0004660 IDA protein farnesyltransferase activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005875 IDA microtubule associated complex
GO:0005965 IDA protein farnesyltransferase complex
GO:0007603 TAS phototransduction, visible light
GO:0008144 IEA drug binding
GO:0008270 IDA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0010035 IEA response to inorganic substance
GO:0014070 IEA response to organic cyclic compound
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0018343 IDA protein farnesylation
GO:0019840 IEA isoprenoid binding
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0034097 IEA response to cytokine
GO:0042060 IEA wound healing
GO:0042277 IEA peptide binding
GO:0043234 IEA protein complex
GO:0045787 IEA positive regulation of cell cycle
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0051770 IEA positive regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027916 fntb farnesyltransferase, CAAX box, beta protein_coding Danio_rerio
ENSMUSG00000033373 Fntb farnesyltransferase, CAAX box, beta protein_coding Mus_musculus

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