C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: farnesyltransferase, CAAX box, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033373 Fntb 10090 + 12:76765589-76921412 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041008 Fntb-001 76837414-76921412 protein_coding
  ENSMUST00000123887 Fntb-003 76840295-76887805 processed_transcript
  ENSMUST00000125842 Fntb-007 76765589-76920659 nonsense_mediated_decay
  ENSMUST00000130605 Fntb-006 76909992-76914651 retained_intron
  ENSMUST00000136939 Fntb-005 76909486-76910325 processed_transcript
  ENSMUST00000137826 Fntb-002 76765598-76920231 protein_coding
  ENSMUST00000151864 Fntb-008 76837433-76844689 processed_transcript
  ENSMUST00000154743 Fntb-004 76887058-76910246 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041008ENSMUST00000137826
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041008 13.667±3.03 8.031±0.97 9.551±0.54 11.747±5.88 10.023±2.22 16.851±2.53 5.139±0.75 5.215±0.22 7.160±6.24 11.109±1.64 4.979±0.37 11.868±4.93 20.871±10.99 4.604±0.43
ENSMUST00000137826 N/A 9.399±0.86 N/A 4.411±0.00 6.418±0.79 N/A N/A N/A N/A N/A N/A 11.228±3.29 5.314±0.00 1.704±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004311 IMP farnesyltranstransferase activity
GO:0004660 ISS protein farnesyltransferase activity
GO:0005515 IEA protein binding
GO:0005875 IEA microtubule associated complex
GO:0005965 ISS protein farnesyltransferase complex
GO:0007275 IEA multicellular organismal development
GO:0008144 IEA drug binding
GO:0008152 IMP metabolic process
GO:0008270 ISS zinc ion binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0010035 IEA response to inorganic substance
GO:0014070 IEA response to organic cyclic compound
GO:0018343 ISS protein farnesylation
GO:0019840 IEA isoprenoid binding
GO:0034097 IEA response to cytokine
GO:0042060 IMP wound healing
GO:0042277 IEA peptide binding
GO:0043234 IEA protein complex
GO:0045787 IEA positive regulation of cell cycle
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0051770 IEA positive regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027916 fntb farnesyltransferase, CAAX box, beta protein_coding Danio_rerio
ENSG00000257365 FNTB farnesyltransferase, CAAX box, beta protein_coding Homo_sapiens

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