C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: farnesyltransferase, CAAX box, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000246166 FNTB-001 ENSG00000257365 9606 + 14:64986720-65062598 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENST00000246166
Transcript ID Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENST00000246166 1.421±0.00 7.058±0.00 7.344±0.00 2.508±0.00 4.173±0.00 3.794±0.00 7.109±2.21 6.335±2.01 9.167±1.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001K4 CIL_0001K4_0002 CGP 14:64986720-65102695

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004311 IEA farnesyltranstransferase activity
GO:0004660 IDA protein farnesyltransferase activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005875 IDA microtubule associated complex
GO:0005965 IDA protein farnesyltransferase complex
GO:0007603 TAS phototransduction, visible light
GO:0008144 IEA drug binding
GO:0008270 IDA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0010035 IEA response to inorganic substance
GO:0014070 IEA response to organic cyclic compound
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0018343 IDA protein farnesylation
GO:0019840 IEA isoprenoid binding
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0034097 IEA response to cytokine
GO:0042060 IEA wound healing
GO:0042277 IEA peptide binding
GO:0043234 IEA protein complex
GO:0045787 IEA positive regulation of cell cycle
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0051770 IEA positive regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041008 Fntb-001 protein_coding Mus_musculus 0 1844
ENSMUST00000125842 Fntb-007 nonsense_mediated_decay Mus_musculus 0 1567
ENSMUST00000137826 Fntb-002 protein_coding Mus_musculus 0 1546
ENSMUST00000154743 Fntb-004 processed_transcript Mus_musculus 0 621
ENSMUST00000123887 Fntb-003 processed_transcript Mus_musculus 0 451
ENSMUST00000151864 Fntb-008 processed_transcript Mus_musculus 0 261
ENSMUST00000130605 Fntb-006 retained_intron Mus_musculus 0 244
ENSMUST00000136939 Fntb-005 processed_transcript Mus_musculus 1.96182e-44 185

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