C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: p21 protein (Cdc42/Rac)-activated kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000259288 PAK6 9606 + 15:40217428-40277486 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000441369 PAK6-201 40217428-40277486 protein_coding
  ENST00000453867 PAK6-202 40217428-40277486 protein_coding
  ENST00000558658 PAK6-001 40217587-40276387 nonsense_mediated_decay
  ENST00000558965 PAK6-003 40217428-40276181 retained_intron
  ENST00000559435 PAK6-004 40218500-40264890 nonsense_mediated_decay
  ENST00000559936 PAK6-002 40217449-40276396 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartLiverMuscleOvaryPlacentaENST00000453867ENST00000558658ENST00000558965
Transcript ID Adrenal Brain Heart Liver Muscle Ovary Placenta
ENST00000453867 0.315±0.00 N/A 0.054±0.00 N/A N/A 0.891±0.00 N/A
ENST00000558658 N/A 1.124±0.00 0.038±0.00 0.020±0.00 N/A N/A N/A
ENST00000558965 N/A N/A N/A N/A 0.185±0.00 N/A 13.447±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0001 VISTA 15:39791359-40393937
CIL_00070K CIL_00070K_0001 CGP 15:40087890-40221136
CIL_0005IH CIL_0005IH_0002 CGP 15:40161023-40277486

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0007010 TAS cytoskeleton organization
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027564 protein_coding Danio_rerio
ENSDARG00000052405 pak6b p21 protein (Cdc42/Rac)-activated kinase 6b protein_coding Danio_rerio
ENSMUSG00000074923 Pak6 p21 protein (Cdc42/Rac)-activated kinase 6 protein_coding Mus_musculus

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