C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cytokine signaling 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000274211 SOCS7 9606 + 17:38352228-38405593 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000612932 SOCS7-001 38352245-38405593 protein_coding
  ENST00000613678 SOCS7-002 38352228-38399648 protein_coding
  ENST00000617360 SOCS7-003 38352551-38399633 retained_intron
  ENST00000617765 SOCS7-004 38352943-38377738 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungMuscleTestisENST00000612932ENST00000613678
Transcript ID Brain Breast Colon Heart Liver Lung Muscle Testis
ENST00000612932 3.953±0.03 N/A 1.004±0.00 0.601±0.38 N/A N/A 0.953±0.04 14.307±3.32
ENST00000613678 N/A 1.489±0.00 N/A N/A 2.765±0.00 1.337±0.00 2.515±0.00 33.908±11.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TL CIL_0000TL_0002 CGP 17:38325530-38405593
CIL_0000SJ CIL_0000SJ_0001 CGP 17:38352228-38512392

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0008150 ND biological_process
GO:0008286 IEA insulin receptor signaling pathway
GO:0009968 IEA negative regulation of signal transduction
GO:0016567 IEA protein ubiquitination
GO:0017124 NAS SH3 domain binding
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045444 IEA fat cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077018 socs7 suppressor of cytokine signaling 7 protein_coding Danio_rerio
ENSDARG00000090553 socs7 suppressor of cytokine signaling 7 protein_coding Danio_rerio
ENSMUSG00000038485 Socs7 suppressor of cytokine signaling 7 protein_coding Mus_musculus

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