C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenoceptor alpha 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000274286 ADRA2B 9606 - 2:96112875-96116245 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000620793 ADRA2B-001 96112875-96116245 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000620793
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000620793 1.256±0.00 1.455±0.00 0.201±0.00 0.125±0.05 0.327±0.29 3.296±0.00 1.451±1.38 1.069±0.85 1.057±0.00 0.098±0.09 1.285±0.41 0.716±0.39 1.445±0.15 2.946±2.23

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000187 IEA activation of MAPK activity
GO:0001525 IEA angiogenesis
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004930 IEA G-protein coupled receptor activity
GO:0004935 IEA adrenergic receptor activity
GO:0004938 IDA alpha2-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007565 IEA female pregnancy
GO:0007596 TAS blood coagulation
GO:0010700 NAS negative regulation of norepinephrine secretion
GO:0016021 IEA integral component of membrane
GO:0030168 TAS platelet activation
GO:0032148 IDA activation of protein kinase B activity
GO:0032811 NAS negative regulation of epinephrine secretion
GO:0035625 IDA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045777 IEA positive regulation of blood pressure
GO:0051379 IDA epinephrine binding
GO:0070474 IEA positive regulation of uterine smooth muscle contraction
GO:0071883 IDA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019819 adra2b adrenergic, alpha-2B-, receptor protein_coding Danio_rerio
ENSDARG00000041008 FP236542.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000058620 Adra2b adrenergic receptor, alpha 2b protein_coding Mus_musculus

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