C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenergic receptor, alpha 2b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000058620 Adra2b 10090 + 2:127363208-127367221 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071902 Adra2b-201 127363286-127367221 protein_coding
  ENSMUST00000104934 Adra2b-001 127363208-127367221 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071902ENSMUST00000104934
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071902 0.250±0.07 0.337±0.19 N/A 0.079±0.00 0.210±0.10 N/A 0.530±0.06 9.872±4.01 0.474±0.12 0.276±0.04 0.291±0.07 0.265±0.12 4.703±0.00 0.070±0.04
ENSMUST00000104934 N/A 0.692±0.27 0.031±0.01 0.145±0.05 0.214±0.00 0.388±0.10 0.477±0.03 21.591±1.92 6.242±5.37 0.283±0.00 0.322±0.02 0.018±0.00 23.344±12.34 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0000187 IEA activation of MAPK activity
GO:0001525 IMP angiogenesis
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004935 IMP adrenergic receptor activity
GO:0004938 IDA alpha2-adrenergic receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007565 IEA female pregnancy
GO:0016021 IEA integral component of membrane
GO:0030168 IEA platelet activation
GO:0032148 IEA activation of protein kinase B activity
GO:0035625 IEA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045777 IEA positive regulation of blood pressure
GO:0051379 IEA epinephrine binding
GO:0070474 IEA positive regulation of uterine smooth muscle contraction
GO:0071883 IEA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019819 adra2b adrenergic, alpha-2B-, receptor protein_coding Danio_rerio
ENSDARG00000041008 FP236542.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000274286 ADRA2B adrenoceptor alpha 2B protein_coding Homo_sapiens

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