C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenoceptor alpha 2B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000620793 ADRA2B-001 ENSG00000274286 9606 - 2:96112875-96116245 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000620793
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000620793 1.256±0.00 1.455±0.00 0.201±0.00 0.125±0.05 0.327±0.29 3.296±0.00 1.451±1.38 1.069±0.85 1.057±0.00 0.098±0.09 1.285±0.41 0.716±0.39 1.445±0.15 2.946±2.23

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000187 IEA activation of MAPK activity
GO:0001525 IEA angiogenesis
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004930 IEA G-protein coupled receptor activity
GO:0004935 IEA adrenergic receptor activity
GO:0004938 IDA alpha2-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007565 IEA female pregnancy
GO:0007596 TAS blood coagulation
GO:0010700 NAS negative regulation of norepinephrine secretion
GO:0016021 IEA integral component of membrane
GO:0030168 TAS platelet activation
GO:0032148 IDA activation of protein kinase B activity
GO:0032811 NAS negative regulation of epinephrine secretion
GO:0035625 IDA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045777 IEA positive regulation of blood pressure
GO:0051379 IDA epinephrine binding
GO:0070474 IEA positive regulation of uterine smooth muscle contraction
GO:0071883 IDA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000071902 Adra2b-201 protein_coding Mus_musculus 0 1310
ENSMUST00000104934 Adra2b-001 protein_coding Mus_musculus 0 1310
ENSMUST00000049545 Adra2c-201 protein_coding Mus_musculus 0 331
ENSDART00000101562 adra2c-001 protein_coding Danio_rerio 0 206
ENSDART00000123912 adra2da-201 protein_coding Danio_rerio 1.4013e-45 189
ENSMUST00000036700 Adra2a-201 protein_coding Mus_musculus 1e-37 163
ENSDART00000060089 FP236542.1-201 protein_coding Danio_rerio 3e-33 148
ENSDART00000018663 adra2b-201 protein_coding Danio_rerio 1e-31 143

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