C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-box 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000093 Tbx2 10090 + 11:85832551-85841948 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000095 Tbx2-001 85832551-85841948 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000095
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000095 5.946±0.97 15.764±3.60 74.317±10.47 3.538±1.98 4.933±2.14 6.797±0.68 2.587±0.50 30.911±4.60 1.188±0.42 108.329±12.05 0.717±0.31 23.039±6.36 5.188±3.01 1.320±0.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000703 CIL_000703_0002 CGP 11:85353167-85841948
CIL_0007RJ CIL_0007RJ_0002 VISTA 11:85412703-86014068
CIL_0007JV CIL_0007JV_0002 UCNEbase 11:85613059-86270571

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003007 IMP heart morphogenesis
GO:0003148 IMP outflow tract septum morphogenesis
GO:0003151 IMP outflow tract morphogenesis
GO:0003203 IMP endocardial cushion morphogenesis
GO:0003256 IDA regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0007521 IMP muscle cell fate determination
GO:0007569 IDA cell aging
GO:0008284 IEA positive regulation of cell proliferation
GO:0035909 IMP aorta morphogenesis
GO:0036302 IMP atrioventricular canal development
GO:0042733 IMP embryonic digit morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0048596 IMP embryonic camera-type eye morphogenesis
GO:0048738 IMP cardiac muscle tissue development
GO:0060021 IGI palate development
GO:0060045 IMP positive regulation of cardiac muscle cell proliferation
GO:0060465 IMP pharynx development
GO:0060560 IMP developmental growth involved in morphogenesis
GO:0060596 IGI mammary placode formation
GO:0090398 ISS cellular senescence
GO:1901208 IMP negative regulation of heart looping
GO:1901211 IMP negative regulation of cardiac chamber formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006120 tbx2b T-box 2b protein_coding Danio_rerio
ENSDARG00000018025 tbx2a T-box gene 2a protein_coding Danio_rerio
ENSG00000121068 TBX2 T-box 2 protein_coding Homo_sapiens

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