C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fer (fms/fps related) protein kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000127 Fer 10090 + 17:63896018-64139494 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000129 Fer-201 63896018-64139494 protein_coding
  ENSMUST00000038080 Fer-202 63937972-64139494 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000129ENSMUST00000038080
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000129 1.025±0.26 0.673±0.32 3.726±0.03 5.464±2.36 1.249±0.27 1.089±0.35 0.638±0.05 0.610±0.00 1.570±0.81 1.361±0.61 1.184±0.18 3.521±2.01 10.759±7.64 1.914±0.20
ENSMUST00000038080 N/A 0.332±0.06 N/A N/A N/A 0.260±0.00 N/A 0.543±0.00 0.358±0.13 0.588±0.00 N/A 0.638±0.06 N/A 4.156±1.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00075K CIL_00075K_0002 CGP 17:63896018-64331916

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 ISS microtubule cytoskeleton organization
GO:0000278 IEA mitotic cell cycle
GO:0000790 ISS nuclear chromatin
GO:0001932 IMP regulation of protein phosphorylation
GO:0003779 IEA actin binding
GO:0004672 IDA protein kinase activity
GO:0004715 ISS non-membrane spanning protein tyrosine kinase activity
GO:0005154 ISS epidermal growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0006935 IMP chemotaxis
GO:0007155 IMP cell adhesion
GO:0007165 IDA signal transduction
GO:0008092 IEA cytoskeletal protein binding
GO:0008157 IPI protein phosphatase 1 binding
GO:0008283 IEA cell proliferation
GO:0008289 ISS lipid binding
GO:0010591 ISS regulation of lamellipodium assembly
GO:0010762 IMP regulation of fibroblast migration
GO:0015629 ISS actin cytoskeleton
GO:0015630 ISS microtubule cytoskeleton
GO:0017137 IEA Rab GTPase binding
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0019221 ISS cytokine-mediated signaling pathway
GO:0019901 IEA protein kinase binding
GO:0030027 ISS lamellipodium
GO:0030054 ISS cell junction
GO:0030335 ISS positive regulation of cell migration
GO:0030838 ISS positive regulation of actin filament polymerization
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0031532 IMP actin cytoskeleton reorganization
GO:0032496 IMP response to lipopolysaccharide
GO:0032869 IDA cellular response to insulin stimulus
GO:0033007 IMP negative regulation of mast cell activation involved in immune response
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0034614 IMP cellular response to reactive oxygen species
GO:0035426 IMP extracellular matrix-cell signaling
GO:0036006 IEA cellular response to macrophage colony-stimulating factor stimulus
GO:0036119 IDA response to platelet-derived growth factor
GO:0038028 IDA insulin receptor signaling pathway via phosphatidylinositol 3-kinase
GO:0038095 IMP Fc-epsilon receptor signaling pathway
GO:0038109 IMP Kit signaling pathway
GO:0042058 ISS regulation of epidermal growth factor receptor signaling pathway
GO:0042503 IEA tyrosine phosphorylation of Stat3 protein
GO:0044331 IMP cell-cell adhesion mediated by cadherin
GO:0045295 IEA gamma-catenin binding
GO:0045296 IEA cadherin binding
GO:0046777 IDA protein autophosphorylation
GO:0048008 IDA platelet-derived growth factor receptor signaling pathway
GO:0050839 IEA cell adhesion molecule binding
GO:0050904 IMP diapedesis
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0070102 IEA interleukin-6-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012196 fer fer (fps/fes related) tyrosine kinase protein_coding Danio_rerio
ENSG00000151422 FER fer (fps/fes related) tyrosine kinase protein_coding Homo_sapiens

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