C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glucagon
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102733 Gcg-001 ENSMUSG00000000394 10090 - 2:62474530-62483650 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonLiverLungOvaryPlacentaENSMUST00000102733
Transcript ID Bladder Brain Breast Colon Liver Lung Ovary Placenta
ENSMUST00000102733 0.014±0.00 0.475±0.09 0.077±0.00 21.287±3.46 0.040±0.02 0.063±0.00 0.185±0.06 0.042±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039X CIL_00039X_0002 CGP 2:62330073-62483650
CIL_0003S0 CIL_0003S0_0003 CGP 2:62474530-62574075

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005179 IBA hormone activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0010737 IMP protein kinase A signaling
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031769 IBA glucagon receptor binding
GO:0032092 IDA positive regulation of protein binding
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0034774 TAS secretory granule lumen
GO:0035774 IDA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0035948 IDA positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0042594 IBA response to starvation
GO:0042802 IEA identical protein binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0045860 IDA positive regulation of protein kinase activity
GO:0050796 IDA regulation of insulin secretion
GO:0051571 IGI positive regulation of histone H3-K4 methylation
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090280 IDA positive regulation of calcium ion import
GO:1900118 IDA negative regulation of execution phase of apoptosis
GO:2001243 IDA negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000375497 GCG-201 protein_coding Homo_sapiens 0 667
ENST00000418842 GCG-001 protein_coding Homo_sapiens 0 706
ENST00000492913 GCG-002 retained_intron Homo_sapiens 0 496
ENST00000497568 GCG-003 retained_intron Homo_sapiens 0 270

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