C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix metallopeptidase 14 (membrane-inserted)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000957 Mmp14 10090 + 14:54431604-54441258 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089688 Mmp14-201 54431604-54441258 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089688
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089688 37.068±22.05 50.891±6.73 61.479±9.93 22.673±4.45 125.103±44.15 65.655±17.20 7.140±2.30 12.456±4.35 17.115±4.25 45.136±3.18 0.422±0.00 153.935±52.88 15.844±8.07 3.089±1.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004Z1 CIL_0004Z1_0003 CGP 14:54426909-54441258
CIL_0004Z6 CIL_0004Z6_0003 CGP 14:54431604-54471497

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IGI ossification
GO:0001525 IEA angiogenesis
GO:0001541 IEA ovarian follicle development
GO:0001666 IEA response to hypoxia
GO:0001935 IEA endothelial cell proliferation
GO:0001958 IGI endochondral ossification
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 IEA integrin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005925 IEA focal adhesion
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006508 IEA proteolysis
GO:0006979 IEA response to oxidative stress
GO:0008270 IEA zinc ion binding
GO:0008584 IEA male gonad development
GO:0009612 IEA response to mechanical stimulus
GO:0009725 IEA response to hormone
GO:0010952 IEA positive regulation of peptidase activity
GO:0014070 IEA response to organic cyclic compound
GO:0016021 IEA integral component of membrane
GO:0016477 IMP cell migration
GO:0016504 IEA peptidase activator activity
GO:0030307 IEA positive regulation of cell growth
GO:0030324 IMP lung development
GO:0030335 IEA positive regulation of cell migration
GO:0030574 IGI collagen catabolic process
GO:0031012 IEA extracellular matrix
GO:0031638 IMP zymogen activation
GO:0035987 IEA endodermal cell differentiation
GO:0035988 IGI chondrocyte proliferation
GO:0043615 IEA astrocyte cell migration
GO:0043627 IEA response to estrogen
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0048754 IMP branching morphogenesis of an epithelial tube
GO:0048771 IEA tissue remodeling
GO:0051895 IEA negative regulation of focal adhesion assembly
GO:0060348 IGI bone development
GO:0097094 IGI craniofacial suture morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002235 mmp14a matrix metalloproteinase 14a (membrane-inserted) protein_coding Danio_rerio
ENSDARG00000008388 mmp14b matrix metalloproteinase 14b (membrane-inserted) protein_coding Danio_rerio
ENSG00000157227 MMP14 matrix metallopeptidase 14 (membrane-inserted) protein_coding Homo_sapiens

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