C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member B3 (aldose reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001642 Akr1b3 10090 - 6:34303934-34317497 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102980 Akr1b3-001 34303934-34317497 protein_coding
  ENSMUST00000126991 Akr1b3-004 34309793-34317430 retained_intron
  ENSMUST00000136559 Akr1b3-003 34307623-34317441 retained_intron
  ENSMUST00000142761 Akr1b3-005 34303934-34306687 retained_intron
  ENSMUST00000154655 Akr1b3-002 34310605-34317459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102980ENSMUST00000136559ENSMUST00000142761
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102980 79.394±13.06 89.909±9.05 358.200±67.52 22.609±11.41 66.346±11.63 39.315±6.15 83.305±10.17 67.555±10.88 12.965±9.25 48.810±2.27 80.534±11.23 74.619±14.18 18.940±11.87 61.303±23.68
ENSMUST00000136559 N/A N/A N/A 0.268±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000142761 N/A N/A N/A N/A 24.200±0.00 17.471±1.02 N/A 33.449±0.00 N/A N/A N/A 37.938±2.74 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002GW CIL_0002GW_0002 CGP 6:34153380-34317497
CIL_0002GX CIL_0002GX_0002 CGP 6:34303934-34368463

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004032 IDA alditol:NADP+ 1-oxidoreductase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0043795 IEA glyceraldehyde oxidoreductase activity
GO:0044597 IEA daunorubicin metabolic process
GO:0044598 IEA doxorubicin metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045598 si:dkey-180p18.9 aldo-keto reductase family 1, member B1 (aldose reductase) protein_coding Danio_rerio
ENSG00000085662 AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) protein_coding Homo_sapiens

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