C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spleen focus forming virus (SFFV) proviral integration oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002111 Spi1 10090 + 2:91082390-91115756 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002180 Spi1-001 91096096-91115756 protein_coding
  ENSMUST00000131400 Spi1-004 91082408-91090310 processed_transcript
  ENSMUST00000132741 Spi1-002 91096780-91113315 protein_coding
  ENSMUST00000169852 Spi1-003 91082390-91114366 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002180ENSMUST00000131400ENSMUST00000132741ENSMUST00000169852
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002180 4.546±2.35 1.179±0.50 3.176±1.27 0.520±0.17 11.118±5.25 3.322±1.88 0.920±0.62 1.440±0.73 6.596±6.55 7.282±0.40 0.281±0.11 2.013±1.01 0.519±0.20 0.247±0.05
ENSMUST00000131400 N/A N/A N/A 0.198±0.00 N/A N/A N/A N/A N/A N/A 0.182±0.14 1.127±0.27 0.177±0.00 0.505±0.11
ENSMUST00000132741 N/A N/A N/A 1.286±0.00 N/A N/A N/A N/A N/A N/A 0.549±0.00 4.607±0.00 1.028±0.00 N/A
ENSMUST00000169852 7.760±0.72 N/A N/A 0.844±0.18 17.635±1.90 4.471±0.00 2.040±0.87 2.533±0.92 9.883±0.00 N/A 0.643±0.00 4.470±2.66 N/A 0.466±0.12

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001047 IEA core promoter binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001944 IMP vasculature development
GO:0002320 IMP lymphoid progenitor cell differentiation
GO:0002573 IMP myeloid leukocyte differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IC transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0030098 IDA lymphocyte differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030225 IDA macrophage differentiation
GO:0030851 IDA granulocyte differentiation
GO:0035019 IDA somatic stem cell maintenance
GO:0043011 IMP myeloid dendritic cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0043966 IEA histone H3 acetylation
GO:0044027 IEA hypermethylation of CpG island
GO:0045347 IDA negative regulation of MHC class II biosynthetic process
GO:0045646 IEA regulation of erythrocyte differentiation
GO:0045814 IEA negative regulation of gene expression, epigenetic
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051525 IPI NFAT protein binding
GO:0060033 IMP anatomical structure regression
GO:0090241 IEA negative regulation of histone H4 acetylation
GO:1902262 IMP apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000767 spi1b spleen focus forming virus (SFFV) proviral integration oncogene spi1b protein_coding Danio_rerio
ENSDARG00000067797 spi1a spleen focus forming virus (SFFV) proviral integration oncogene spi1a protein_coding Danio_rerio
ENSG00000066336 SPI1 Spi-1 proto-oncogene protein_coding Homo_sapiens

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