C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kelch-like ECH-associated protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003308 Keap1 10090 - 9:21229730-21239332 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049567 Keap1-201 21229730-21239332 protein_coding
  ENSMUST00000164812 Keap1-202 21229730-21239332 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049567ENSMUST00000164812
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049567 22.004±1.28 14.611±9.32 14.760±0.36 22.773±10.97 17.364±6.16 6.641±0.97 10.042±4.84 14.064±4.42 9.893±2.23 15.734±7.16 14.361±4.81 18.757±7.47 13.447±4.75 20.999±4.26
ENSMUST00000164812 3.091±0.41 9.104±3.09 1.555±0.15 1.735±0.22 6.207±3.01 3.568±0.29 2.552±0.36 2.109±0.74 2.407±0.66 4.209±1.50 3.785±0.57 6.123±2.08 1.360±0.17 2.666±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004FB CIL_0004FB_0002 CGP 9:21165714-21239332
CIL_000777 CIL_000777_0003 CGP 9:21229730-21248443

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IPI cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005815 IEA microtubule organizing center
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0010499 ISS proteasomal ubiquitin-independent protein catabolic process
GO:0016567 ISS protein ubiquitination
GO:0030496 IEA midbody
GO:0031463 ISS Cul3-RING ubiquitin ligase complex
GO:0045604 IMP regulation of epidermal cell differentiation
GO:0071353 IDA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074634 keap1b kelch-like ECH-associated protein 1b protein_coding Danio_rerio
ENSG00000079999 KEAP1 kelch-like ECH-associated protein 1 protein_coding Homo_sapiens

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