C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribosomal protein S6 kinase polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003644 Rps6ka1 10090 - 4:133847290-133887797 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003741 Rps6ka1-002 133847294-133887784 protein_coding
  ENSMUST00000105894 Rps6ka1-001 133847290-133887797 protein_coding
  ENSMUST00000129636 Rps6ka1-005 133860165-133861042 retained_intron
  ENSMUST00000137486 Rps6ka1-004 133848052-133873039 protein_coding
  ENSMUST00000157067 Rps6ka1-006 133847825-133872313 protein_coding
  ENSMUST00000168974 Rps6ka1-003 133847294-133874731 protein_coding
  ENSMUST00000173961 Rps6ka1-009 133871964-133887574 processed_transcript
  ENSMUST00000173989 Rps6ka1-007 133850557-133860930 retained_intron
  ENSMUST00000174481 Rps6ka1-008 133847963-133886283 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003741ENSMUST00000105894ENSMUST00000129636ENSMUST00000137486ENSMUST00000157067ENSMUST00000168974ENSMUST00000173989ENSMUST00000174481
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003741 N/A 2.798±0.00 N/A N/A N/A N/A N/A N/A 0.794±0.00 N/A N/A N/A N/A N/A
ENSMUST00000105894 4.832±2.17 7.616±1.09 4.581±0.59 4.466±2.13 7.352±3.31 84.534±4.56 0.905±0.22 9.388±2.10 4.044±1.66 18.645±3.81 1.257±0.50 10.257±3.53 12.180±2.49 1.047±0.00
ENSMUST00000129636 N/A N/A N/A 18.028±0.00 N/A N/A N/A N/A N/A N/A N/A 20.605±0.00 51.403±3.26 31.560±0.00
ENSMUST00000137486 N/A N/A N/A 5.168±0.00 8.216±4.89 N/A 0.984±0.32 N/A 7.187±2.11 7.589±0.00 0.774±0.00 6.519±0.00 18.377±2.60 4.415±0.00
ENSMUST00000157067 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.608±0.00 1.741±0.00 N/A 12.833±5.14
ENSMUST00000168974 3.428±0.52 N/A 2.617±0.58 N/A 3.158±0.32 N/A 1.639±0.28 N/A 7.874±3.90 N/A 0.824±0.07 3.869±1.02 6.047±0.00 3.840±0.00
ENSMUST00000173989 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.701±1.72 N/A N/A
ENSMUST00000174481 N/A N/A N/A N/A 3.168±0.00 N/A 0.640±0.00 N/A N/A N/A N/A 6.055±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T4 CIL_0007T4_0002 VISTA 4:133429051-134030305

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005819 IDA spindle
GO:0006468 IEA protein phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0043027 IEA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:2000491 ISS positive regulation of hepatic stellate cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033437 rps6ka1 ribosomal protein S6 kinase a, polypeptide 1 protein_coding Danio_rerio
ENSG00000117676 RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 protein_coding Homo_sapiens

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