C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin induced gene 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003818 Insig2-002 ENSMUSG00000003721 10090 - 1:121304353-121328024 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003818
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003818 7.005±3.16 5.399±1.67 6.028±0.80 8.688±4.79 7.907±3.03 7.056±4.05 5.396±0.26 6.179±4.30 5.999±4.83 5.686±0.00 7.845±3.00 2.352±0.62 2.921±0.07 7.327±1.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KO CIL_0007KO_0002 UCNEbase 1:120886247-121392907

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0006641 IGI triglyceride metabolic process
GO:0006695 IGI cholesterol biosynthetic process
GO:0006991 IDA response to sterol depletion
GO:0008134 IEA transcription factor binding
GO:0008203 IGI cholesterol metabolic process
GO:0010894 IGI negative regulation of steroid biosynthetic process
GO:0016126 IGI sterol biosynthetic process
GO:0032868 IEA response to insulin
GO:0032933 IEA SREBP signaling pathway
GO:0032937 IEA SREBP-SCAP-Insig complex
GO:0033993 IEA response to lipid
GO:0042472 IGI inner ear morphogenesis
GO:0042474 IGI middle ear morphogenesis
GO:0045717 IGI negative regulation of fatty acid biosynthetic process
GO:0060021 IGI palate development
GO:0060363 IGI cranial suture morphogenesis
GO:0070542 IEA response to fatty acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000245787 INSIG2-001 protein_coding Homo_sapiens 0 837
ENST00000411929 INSIG2-007 nonsense_mediated_decay Homo_sapiens 0 542
ENST00000467223 INSIG2-004 processed_transcript Homo_sapiens 0 542
ENST00000471186 INSIG2-003 processed_transcript Homo_sapiens 0 337
ENST00000479999 INSIG2-006 processed_transcript Homo_sapiens 0 387
ENST00000485520 INSIG2-002 processed_transcript Homo_sapiens 0 542
ENST00000488995 INSIG2-005 processed_transcript Homo_sapiens 0 411
ENST00000614681 INSIG2-201 protein_coding Homo_sapiens 0 830

Loading