C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deoxyribonuclease II alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003812 Dnase2a 10090 + 8:84908560-84922915 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003910 Dnase2a-001 84908560-84911469 protein_coding
  ENSMUST00000109744 Dnase2a-002 84908560-84911708 protein_coding
  ENSMUST00000128400 Dnase2a-003 84908721-84914521 processed_transcript
  ENSMUST00000134569 Dnase2a-005 84908731-84909964 protein_coding
  ENSMUST00000135219 Dnase2a-008 84909835-84911461 processed_transcript
  ENSMUST00000145292 Dnase2a-006 84908690-84909925 protein_coding
  ENSMUST00000148573 Dnase2a-009 84913391-84922915 processed_transcript
  ENSMUST00000153215 Dnase2a-007 84908647-84909468 retained_intron
  ENSMUST00000155942 Dnase2a-004 84908647-84909200 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003910ENSMUST00000109744ENSMUST00000128400ENSMUST00000148573ENSMUST00000155942
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003910 12.183±1.69 5.582±1.36 5.922±0.04 17.118±3.63 6.799±1.12 1.893±0.40 8.079±1.23 8.500±1.50 10.260±1.06 2.143±0.42 6.750±1.90 11.699±3.91 0.596±0.09
ENSMUST00000109744 N/A 3.045±0.66 N/A 5.837±0.00 2.131±0.00 0.809±0.10 1.745±0.26 N/A 2.525±0.21 0.390±0.00 1.943±0.33 N/A N/A
ENSMUST00000128400 N/A N/A 0.516±0.00 N/A N/A 0.214±0.00 N/A 0.781±0.11 N/A 0.242±0.03 1.120±0.00 N/A N/A
ENSMUST00000148573 N/A N/A 2.156±0.23 N/A N/A N/A N/A N/A N/A 0.459±0.00 4.905±1.45 5.415±1.29 1.866±0.00
ENSMUST00000155942 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.957±0.44 53.513±9.98 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZV CIL_0007ZV_0002 VISTA 8:84428902-85032705
CIL_0007VV CIL_0007VV_0002 VISTA 8:84441926-85045230

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004520 IEA endodeoxyribonuclease activity
GO:0004531 IDA deoxyribonuclease II activity
GO:0005622 IBA intracellular
GO:0005764 TAS lysosome
GO:0006308 IMP DNA catabolic process
GO:0006309 IBA apoptotic DNA fragmentation
GO:0030218 IMP erythrocyte differentiation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073893 dnase2 deoxyribonuclease II, lysosomal protein_coding Danio_rerio
ENSG00000105612 DNASE2 deoxyribonuclease II, lysosomal protein_coding Homo_sapiens

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