C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calreticulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003814 Calr 10090 - 8:84841850-84846934 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003912 Calr-001 84841850-84846934 protein_coding
  ENSMUST00000125998 Calr-003 84845750-84846826 retained_intron
  ENSMUST00000128028 Calr-002 84845437-84846830 retained_intron
  ENSMUST00000154774 Calr-004 84842596-84844916 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003912ENSMUST00000154774
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003912 142.139±28.28 86.871±3.19 147.850±6.08 122.749±51.14 114.145±13.15 145.724±15.68 76.922±9.72 167.606±10.79 245.129±36.52 112.866±13.91 38.021±2.46 206.067±29.41 581.104±164.56 192.127±22.06
ENSMUST00000154774 N/A N/A N/A 304.766±0.00 N/A N/A N/A N/A N/A N/A N/A 573.345±553.64 1574.708±1297.45 1709.020±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZV CIL_0007ZV_0002 VISTA 8:84428902-85032705
CIL_0007VV CIL_0007VV_0002 VISTA 8:84441926-85045230

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001669 IEA acrosomal vesicle
GO:0001948 IEA glycoprotein binding
GO:0002502 IMP peptide antigen assembly with MHC class I protein complex
GO:0003729 IDA mRNA binding
GO:0005178 IEA integrin binding
GO:0005506 IEA iron ion binding
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005788 IDA endoplasmic reticulum lumen
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0005844 IDA polysome
GO:0005925 IEA focal adhesion
GO:0006611 IEA protein export from nucleus
GO:0007050 IEA cell cycle arrest
GO:0007283 IEA spermatogenesis
GO:0008284 IEA positive regulation of cell proliferation
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0010628 IMP positive regulation of gene expression
GO:0016020 IEA membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0017148 IEA negative regulation of translation
GO:0030246 IDA carbohydrate binding
GO:0030866 IDA cortical actin cytoskeleton organization
GO:0031012 IEA extracellular matrix
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032355 IEA response to estradiol
GO:0033144 IEA negative regulation of intracellular steroid hormone receptor signaling pathway
GO:0033574 IEA response to testosterone
GO:0034504 IMP protein localization to nucleus
GO:0040020 IDA regulation of meiosis
GO:0042277 IEA peptide binding
GO:0042493 IEA response to drug
GO:0042562 IEA hormone binding
GO:0042824 IMP MHC class I peptide loading complex
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IEA protein complex
GO:0044822 IEA poly(A) RNA binding
GO:0045335 TAS phagocytic vesicle
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045740 IEA positive regulation of DNA replication
GO:0045787 IMP positive regulation of cell cycle
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0048387 IEA negative regulation of retinoic acid receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050681 IEA androgen receptor binding
GO:0050766 IMP positive regulation of phagocytosis
GO:0050821 IDA protein stabilization
GO:0055007 IEA cardiac muscle cell differentiation
GO:0061077 IEA chaperone-mediated protein folding
GO:0070062 IEA extracellular vesicular exosome
GO:0071285 IEA cellular response to lithium ion
GO:0071310 IEA cellular response to organic substance
GO:0090398 IMP cellular senescence
GO:1900026 IEA positive regulation of substrate adhesion-dependent cell spreading
GO:2000510 IEA positive regulation of dendritic cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076290 calrl2 calreticulin, like 2 protein_coding Danio_rerio
ENSG00000179218 CALR calreticulin protein_coding Homo_sapiens

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