C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thymoma viral proto-oncogene 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004056 Akt2 10090 + 7:27591552-27640826 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051356 Akt2-003 27605858-27639453 protein_coding
  ENSMUST00000085917 Akt2-013 27608662-27638170 protein_coding
  ENSMUST00000108342 Akt2-005 27592458-27633266 protein_coding
  ENSMUST00000108343 Akt2-002 27605817-27639448 protein_coding
  ENSMUST00000108344 Akt2-001 27591552-27640826 protein_coding
  ENSMUST00000128540 Akt2-004 27592368-27628845 protein_coding
  ENSMUST00000136962 Akt2-009 27607748-27633246 protein_coding
  ENSMUST00000136981 Akt2-012 27636053-27637443 retained_intron
  ENSMUST00000138459 Akt2-006 27596830-27618233 protein_coding
  ENSMUST00000142365 Akt2-010 27608004-27618286 protein_coding
  ENSMUST00000143347 Akt2-011 27628525-27634811 retained_intron
  ENSMUST00000143499 Akt2-008 27605797-27628869 protein_coding
  ENSMUST00000147263 Akt2-007 27593546-27616346 processed_transcript
  ENSMUST00000167435 Akt2-201 27591746-27639450 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051356ENSMUST00000085917ENSMUST00000108343ENSMUST00000108344ENSMUST00000128540ENSMUST00000167435
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051356 65.976±19.99 29.389±4.75 17.731±5.36 11.190±3.21 29.946±13.00 6.212±1.04 28.282±2.65 19.423±3.17 12.831±4.03 15.504±4.07 47.176±13.89 20.756±9.99 23.044±9.84 9.772±3.06
ENSMUST00000085917 N/A N/A N/A N/A 53.216±0.00 N/A N/A N/A N/A N/A N/A 21.890±4.63 13.316±0.00 N/A
ENSMUST00000108343 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.067±0.00
ENSMUST00000108344 6.015±0.00 9.926±0.67 3.958±0.45 2.951±0.16 6.081±0.33 2.402±0.35 4.057±0.00 3.541±0.32 2.437±0.93 5.699±0.39 6.156±0.00 5.789±1.66 N/A 2.145±0.65
ENSMUST00000128540 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 80.586±0.00 N/A
ENSMUST00000167435 30.396±9.15 32.636±3.46 10.732±0.74 9.374±0.39 38.708±1.61 12.716±1.72 23.298±4.53 15.264±1.19 15.174±5.34 21.700±3.62 31.810±4.77 30.992±2.20 11.485±1.28 12.998±1.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005886 IMP plasma membrane
GO:0005938 IMP cell cortex
GO:0005978 IEA glycogen biosynthetic process
GO:0006006 IEA glucose metabolic process
GO:0006417 IEA regulation of translation
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0008286 IDA insulin receptor signaling pathway
GO:0008643 IEA carbohydrate transport
GO:0010748 IEA negative regulation of plasma membrane long-chain fatty acid transport
GO:0010907 IEA positive regulation of glucose metabolic process
GO:0031340 IMP positive regulation of vesicle fusion
GO:0032000 IEA positive regulation of fatty acid beta-oxidation
GO:0032287 IMP peripheral nervous system myelin maintenance
GO:0032587 IMP ruffle membrane
GO:0032859 IGI activation of Ral GTPase activity
GO:0032869 IDA cellular response to insulin stimulus
GO:0045725 IEA positive regulation of glycogen biosynthetic process
GO:0046326 IEA positive regulation of glucose import
GO:0065002 IMP intracellular protein transmembrane transport
GO:0072659 IGI protein localization to plasma membrane
GO:0090314 IMP positive regulation of protein targeting to membrane
GO:2000147 IEA positive regulation of cell motility
GO:2001275 IGI positive regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011219 akt2 v-akt murine thymoma viral oncogene homolog 2 protein_coding Danio_rerio
ENSDARG00000026797 akt2l v-akt murine thymoma viral oncogene homolog 2, like protein_coding Danio_rerio
ENSG00000105221 AKT2 v-akt murine thymoma viral oncogene homolog 2 protein_coding Homo_sapiens

Loading