C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thymoma viral proto-oncogene 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000167435 Akt2-201 ENSMUSG00000004056 10090 + 7:27591746-27639450 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000167435
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000167435 30.396±9.15 32.636±3.46 10.732±0.74 9.374±0.39 38.708±1.61 12.716±1.72 23.298±4.53 15.264±1.19 15.174±5.34 21.700±3.62 31.810±4.77 30.992±2.20 11.485±1.28 12.998±1.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IMP plasma membrane
GO:0005938 IMP cell cortex
GO:0005978 IEA glycogen biosynthetic process
GO:0006006 IEA glucose metabolic process
GO:0006417 IEA regulation of translation
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0008286 IDA insulin receptor signaling pathway
GO:0008643 IEA carbohydrate transport
GO:0031340 IMP positive regulation of vesicle fusion
GO:0032287 IMP peripheral nervous system myelin maintenance
GO:0032587 IMP ruffle membrane
GO:0032859 IGI activation of Ral GTPase activity
GO:0032869 IDA cellular response to insulin stimulus
GO:0065002 IMP intracellular protein transmembrane transport
GO:0072659 IGI protein localization to plasma membrane
GO:0090314 IMP positive regulation of protein targeting to membrane
GO:2001275 IGI positive regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000311278 AKT2-027 protein_coding Homo_sapiens 0 1114
ENST00000358335 AKT2-042 protein_coding Homo_sapiens 0 409
ENST00000391844 AKT2-026 nonsense_mediated_decay Homo_sapiens 0 1871
ENST00000391845 AKT2-017 processed_transcript Homo_sapiens 0 791
ENST00000392037 AKT2-014 protein_coding Homo_sapiens 0 634
ENST00000392038 AKT2-001 protein_coding Homo_sapiens 0 2117
ENST00000416362 AKT2-010 protein_coding Homo_sapiens 0 634
ENST00000416994 AKT2-008 protein_coding Homo_sapiens 0 484
ENST00000423127 AKT2-007 protein_coding Homo_sapiens 0 579
ENST00000424901 AKT2-201 protein_coding Homo_sapiens 0 1254
ENST00000427375 AKT2-011 protein_coding Homo_sapiens 0 353
ENST00000441941 AKT2-012 protein_coding Homo_sapiens 0 817
ENST00000452077 AKT2-005 protein_coding Homo_sapiens 0 636
ENST00000456441 AKT2-006 protein_coding Homo_sapiens 0 538
ENST00000476247 AKT2-041 protein_coding Homo_sapiens 0 425
ENST00000476266 AKT2-002 retained_intron Homo_sapiens 0 1533
ENST00000480878 AKT2-037 processed_transcript Homo_sapiens 0 507
ENST00000483166 AKT2-003 retained_intron Homo_sapiens 0 867
ENST00000486368 AKT2-033 protein_coding Homo_sapiens 0 719
ENST00000486647 AKT2-023 processed_transcript Homo_sapiens 0 315
ENST00000487537 AKT2-015 retained_intron Homo_sapiens 0 532
ENST00000489375 AKT2-019 nonsense_mediated_decay Homo_sapiens 0 383
ENST00000491778 AKT2-034 nonsense_mediated_decay Homo_sapiens 0 209
ENST00000492463 AKT2-013 nonsense_mediated_decay Homo_sapiens 0 819
ENST00000496089 AKT2-022 retained_intron Homo_sapiens 0 664
ENST00000497948 AKT2-021 protein_coding Homo_sapiens 0 327
ENST00000537834 AKT2-016 retained_intron Homo_sapiens 0 922
ENST00000578123 AKT2-029 protein_coding Homo_sapiens 0 628
ENST00000578282 AKT2-040 retained_intron Homo_sapiens 0 233
ENST00000578310 AKT2-036 protein_coding Homo_sapiens 4e-29 130
ENST00000578615 AKT2-035 protein_coding Homo_sapiens 0 889
ENST00000579047 AKT2-025 protein_coding Homo_sapiens 0 1742
ENST00000579345 AKT2-039 retained_intron Homo_sapiens 0 544
ENST00000580747 AKT2-032 protein_coding Homo_sapiens 0 484
ENST00000580878 AKT2-038 retained_intron Homo_sapiens 0 446
ENST00000583859 AKT2-030 protein_coding Homo_sapiens 0 499
ENST00000584288 AKT2-024 nonsense_mediated_decay Homo_sapiens 0 1855
ENST00000596634 AKT2-045 protein_coding Homo_sapiens 0 695
ENST00000601166 AKT2-044 nonsense_mediated_decay Homo_sapiens 0 619

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