C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, R type, alpha 1E subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004110 Cacna1e 10090 - 1:154390731-154884501 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004214 Cacna1e-201 154392519-154725920 protein_coding
  ENSMUST00000186256 Cacna1e-005 154882166-154884024 retained_intron
  ENSMUST00000187541 Cacna1e-001 154390731-154726356 protein_coding
  ENSMUST00000188321 Cacna1e-003 154699089-154884501 retained_intron
  ENSMUST00000188384 Cacna1e-004 154469052-154476696 retained_intron
  ENSMUST00000188965 Cacna1e-002 154481075-154816941 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004214ENSMUST00000187541ENSMUST00000188321ENSMUST00000188384ENSMUST00000188965
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004214 0.262±0.06 0.026±0.01 N/A N/A 0.169±0.03 0.175±0.05 0.023±0.00 0.055±0.00 0.018±0.01 0.066±0.00 0.005±0.00 0.232±0.07 0.015±0.01 0.075±0.04
ENSMUST00000187541 0.602±0.00 0.039±0.00 0.015±0.00 4.260±2.05 0.459±0.00 N/A 0.015±0.00 0.050±0.03 0.023±0.01 0.161±0.04 0.008±0.00 0.193±0.09 0.013±0.00 N/A
ENSMUST00000188321 0.273±0.00 0.155±0.05 N/A N/A 0.751±0.00 N/A 0.084±0.01 0.155±0.05 0.124±0.06 N/A 0.021±0.00 0.434±0.00 0.017±0.00 N/A
ENSMUST00000188384 N/A N/A N/A N/A N/A N/A N/A N/A 0.009±0.00 N/A N/A N/A N/A 0.212±0.00
ENSMUST00000188965 N/A 0.017±0.00 N/A N/A N/A N/A N/A 0.018±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001662 IMP behavioral fear response
GO:0002027 IMP regulation of heart rate
GO:0005245 IMP voltage-gated calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005886 IBA plasma membrane
GO:0005891 TAS voltage-gated calcium channel complex
GO:0006816 IMP calcium ion transport
GO:0007268 IBA synaptic transmission
GO:0007626 IMP locomotory behavior
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0008542 IMP visual learning
GO:0019226 IMP transmission of nerve impulse
GO:0019233 IMP sensory perception of pain
GO:0030317 IMP sperm motility
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042593 IMP glucose homeostasis
GO:0042596 IMP fear response
GO:0048265 IMP response to pain
GO:0048266 IMP behavioral response to pain
GO:0050877 IMP neurological system process
GO:0061178 IMP regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070509 IBA calcium ion import
GO:0070588 IMP calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential
GO:0090273 IMP regulation of somatostatin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062346 cacna1r calcium channel, voltage-dependent, alpha 1R subunit protein_coding Danio_rerio
ENSDARG00000095614 CACNA1E (2 of 2) calcium channel, voltage-dependent, R type, alpha 1E subunit protein_coding Danio_rerio
ENSG00000198216 CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit protein_coding Homo_sapiens

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