C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nestin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004891 Nes 10090 + 3:87971078-87980451 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090973 Nes-001 87971093-87980451 protein_coding
  ENSMUST00000159830 Nes-002 87971078-87973391 retained_intron
  ENSMUST00000160694 Nes-003 87971129-87980451 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000090973ENSMUST00000159830ENSMUST00000160694
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000090973 3.765±0.57 2.000±0.28 1.609±0.06 11.332±0.40 2.361±0.44 0.506±0.19 2.761±0.88 3.202±0.63 0.685±0.29 12.048±1.99 3.985±0.86 3.931±3.64 4.674±3.79 0.161±0.10
ENSMUST00000159830 N/A 1.388±0.06 N/A N/A 1.675±0.42 0.308±0.00 N/A N/A N/A N/A N/A 1.996±0.47 N/A N/A
ENSMUST00000160694 1.362±0.00 1.346±0.84 0.198±0.00 3.947±2.58 0.985±0.41 0.466±0.32 1.178±0.64 1.064±0.46 0.279±0.08 3.496±1.98 2.237±0.38 2.442±1.54 3.664±2.56 0.495±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000850 CIL_000850_0002 VISTA 3:87682625-88286876
CIL_0008JO CIL_0008JO_0002 VISTA 3:87838105-88441065

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IEA G2/M transition of mitotic cell cycle
GO:0005198 IEA structural molecule activity
GO:0005622 IDA intracellular
GO:0005737 IDA cytoplasm
GO:0005882 IDA intermediate filament
GO:0007399 IDA nervous system development
GO:0007420 ISS brain development
GO:0019215 ISS intermediate filament binding
GO:0030844 ISS positive regulation of intermediate filament depolymerization
GO:0031076 ISS embryonic camera-type eye development
GO:0032091 IEA negative regulation of protein binding
GO:0043086 IEA negative regulation of catalytic activity
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045111 IEA intermediate filament cytoskeleton
GO:0048858 IMP cell projection morphogenesis
GO:0072089 IEA stem cell proliferation
GO:2000179 ISS positive regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088805 nes nestin protein_coding Danio_rerio
ENSG00000132688 NES nestin protein_coding Homo_sapiens

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