C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zona pellucida glycoprotein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004948 Zp3 10090 + 5:135980099-135988624 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005073 Zp3-001 135980099-135988624 protein_coding
  ENSMUST00000131563 Zp3-002 135980168-135987292 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000005073ENSMUST00000131563
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000005073 0.031±0.01 0.033±0.00 0.051±0.02 0.022±0.00 0.030±0.02 0.027±0.01 0.017±0.01 0.054±0.01 64.958±27.23 0.026±0.01 0.329±0.18
ENSMUST00000131563 N/A N/A N/A N/A N/A 0.035±0.00 N/A N/A N/A N/A 0.053±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006E7 CIL_0006E7_0002 CGP 5:135960211-135988624
CIL_0006E4 CIL_0006E4_0002 CGP 5:135980099-136032872

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001669 ISS acrosomal vesicle
GO:0001809 IDA positive regulation of type IV hypersensitivity
GO:0001825 IMP blastocyst formation
GO:0002081 IDA outer acrosomal membrane
GO:0002455 IDA humoral immune response mediated by circulating immunoglobulin
GO:0002687 IDA positive regulation of leukocyte migration
GO:0002922 ISS positive regulation of humoral immune response
GO:0004871 IDA signal transducer activity
GO:0005384 IDA manganese ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 ISS extracellular space
GO:0005737 IDA cytoplasm
GO:0005771 IDA multivesicular body
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006828 IDA manganese ion transport
GO:0006886 IMP intracellular protein transport
GO:0007339 IMP binding of sperm to zona pellucida
GO:0010513 IDA positive regulation of phosphatidylinositol biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0030141 IDA secretory granule
GO:0030246 ISS carbohydrate binding
GO:0031012 IDA extracellular matrix
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0032753 IDA positive regulation of interleukin-4 production
GO:0035556 IDA intracellular signal transduction
GO:0035803 IMP egg coat formation
GO:0042102 IDA positive regulation of T cell proliferation
GO:0045860 ISS positive regulation of protein kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048015 IMP phosphatidylinositol-mediated signaling
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048599 IMP oocyte development
GO:0050729 IDA positive regulation of inflammatory response
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0070528 ISS protein kinase C signaling
GO:0071421 IDA manganese ion transmembrane transport
GO:0090280 IDA positive regulation of calcium ion import
GO:2000344 IDA positive regulation of acrosome reaction
GO:2000368 ISS positive regulation of acrosomal vesicle exocytosis
GO:2000386 IMP positive regulation of ovarian follicle development
GO:2000388 IMP positive regulation of antral ovarian follicle growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016908 zgc:171779 zgc:171779 protein_coding Danio_rerio
ENSDARG00000039828 zp3b zona pellucida glycoprotein 3b protein_coding Danio_rerio
ENSDARG00000042129 zp3a.1 zona pellucida glycoprotein 3a, tandem duplicate 1 protein_coding Danio_rerio
ENSDARG00000042130 zp3a.2 zona pellucida glycoprotein 3a, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000087209 zp3.2 zona pellucida glycoprotein 3, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000089352 zp3.2 zona pellucida glycoprotein 3, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000089690 CABZ01044980.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000090768 zgc:173556 zgc:173556 protein_coding Danio_rerio
ENSG00000146707 POMZP3 POM121 and ZP3 fusion protein_coding Homo_sapiens
ENSG00000188372 ZP3 zona pellucida glycoprotein 3 (sperm receptor) protein_coding Homo_sapiens

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