C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005360 Slc1a3 10090 - 15:8634124-8710764 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005493 Slc1a3-001 8634124-8710764 protein_coding
  ENSMUST00000125997 Slc1a3-006 8634726-8651506 retained_intron
  ENSMUST00000126747 Slc1a3-005 8708743-8709588 processed_transcript
  ENSMUST00000128879 Slc1a3-008 8642256-8643247 retained_intron
  ENSMUST00000129325 Slc1a3-007 8687898-8710496 retained_intron
  ENSMUST00000133309 Slc1a3-002 8707610-8710481 retained_intron
  ENSMUST00000153455 Slc1a3-003 8680521-8710416 processed_transcript
  ENSMUST00000157065 Slc1a3-004 8686016-8710409 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005493ENSMUST00000125997ENSMUST00000128879ENSMUST00000129325
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005493 10.057±2.28 4.086±1.43 1.062±0.05 26.525±9.50 8.108±1.97 0.386±0.25 0.646±0.28 1.270±0.18 0.084±0.07 5.933±1.49 0.224±0.15 5.277±1.84 0.713±0.73 0.171±0.06
ENSMUST00000125997 1.109±0.00 N/A N/A N/A 2.207±0.00 N/A 0.106±0.00 N/A 0.042±0.02 0.850±0.06 0.111±0.00 0.973±0.22 0.156±0.15 0.115±0.00
ENSMUST00000128879 N/A N/A N/A N/A N/A 0.912±0.17 N/A N/A 0.102±0.00 N/A N/A N/A N/A N/A
ENSMUST00000129325 N/A N/A N/A N/A N/A N/A N/A N/A 0.062±0.00 N/A N/A N/A 0.064±0.00 0.141±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005313 IEA L-glutamate transmembrane transporter activity
GO:0005314 IDA high-affinity glutamate transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0006536 IMP glutamate metabolic process
GO:0006537 IMP glutamate biosynthetic process
GO:0007605 IMP sensory perception of sound
GO:0009416 IMP response to light stimulus
GO:0009449 IMP gamma-aminobutyric acid biosynthetic process
GO:0009611 IMP response to wounding
GO:0009986 IDA cell surface
GO:0010035 ISO response to inorganic substance
GO:0015813 IDA L-glutamate transport
GO:0016021 IEA integral component of membrane
GO:0016595 IDA glutamate binding
GO:0016597 IDA amino acid binding
GO:0017153 IEA sodium:dicarboxylate symporter activity
GO:0021545 IMP cranial nerve development
GO:0031223 IMP auditory behavior
GO:0042493 IMP response to drug
GO:0042995 IDA cell projection
GO:0043025 IDA neuronal cell body
GO:0043200 ISO response to amino acid
GO:0043205 IDA fibril
GO:0046677 IMP response to antibiotic
GO:0048667 IMP cell morphogenesis involved in neuron differentiation
GO:0050806 IMP positive regulation of synaptic transmission
GO:0050885 IMP neuromuscular process controlling balance
GO:0051938 IMP L-glutamate import
GO:0055085 IEA transmembrane transport
GO:0070779 IEA D-aspartate import

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010096 slc1a6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 protein_coding Danio_rerio
ENSG00000079215 SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 protein_coding Homo_sapiens

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