C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000079215 SLC1A3 9606 + 5:36606355-36688334 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265113 SLC1A3-001 36606355-36688334 protein_coding
  ENST00000381918 SLC1A3-201 36608329-36688332 protein_coding
  ENST00000416645 SLC1A3-009 36606617-36612908 protein_coding
  ENST00000502864 SLC1A3-014 36608490-36630473 processed_transcript
  ENST00000504121 SLC1A3-008 36606611-36608698 retained_intron
  ENST00000505202 SLC1A3-010 36606890-36629588 protein_coding
  ENST00000505376 SLC1A3-015 36670821-36677127 processed_transcript
  ENST00000506178 SLC1A3-017 36680347-36686233 retained_intron
  ENST00000506725 SLC1A3-005 36606617-36613487 processed_transcript
  ENST00000509272 SLC1A3-013 36613099-36671234 processed_transcript
  ENST00000512374 SLC1A3-003 36606611-36609299 retained_intron
  ENST00000513646 SLC1A3-011 36608178-36629588 protein_coding
  ENST00000513903 SLC1A3-007 36606439-36629572 protein_coding
  ENST00000514563 SLC1A3-012 36612810-36671184 processed_transcript
  ENST00000612708 SLC1A3-202 36606355-36688332 protein_coding
  ENST00000613445 SLC1A3-203 36606355-36688332 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265113ENST00000381918ENST00000505376ENST00000506178ENST00000512374ENST00000514563ENST00000612708
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265113 N/A N/A N/A 49.267±15.00 2.372±0.18 N/A 3.082±0.74 N/A 0.934±0.00 2.459±0.00 1.256±0.05 1.204±0.45 3.417±0.70 N/A
ENST00000381918 5.600±0.00 0.386±0.00 0.040±0.00 99.666±0.00 7.276±0.00 0.405±0.00 13.239±0.00 1.950±0.00 0.894±0.38 1.851±0.00 5.386±0.00 1.109±0.81 2.100±0.00 1.022±0.00
ENST00000505376 N/A N/A 0.451±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000506178 N/A N/A N/A N/A 8.869±0.00 N/A N/A N/A N/A N/A N/A 5.945±0.00 N/A N/A
ENST00000512374 N/A N/A N/A N/A N/A N/A 3.656±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000514563 N/A N/A 0.128±0.00 N/A N/A N/A N/A 2.740±0.00 N/A N/A N/A N/A N/A N/A
ENST00000612708 N/A 0.439±0.00 N/A N/A N/A N/A N/A 0.205±0.00 N/A 0.693±0.00 N/A N/A N/A 0.081±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001504 TAS neurotransmitter uptake
GO:0005313 IDA L-glutamate transmembrane transporter activity
GO:0005314 IEA high-affinity glutamate transmembrane transporter activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006536 IEA glutamate metabolic process
GO:0006537 IEA glutamate biosynthetic process
GO:0006811 TAS ion transport
GO:0006835 IEA dicarboxylic acid transport
GO:0007268 TAS synaptic transmission
GO:0007605 IEA sensory perception of sound
GO:0009416 IEA response to light stimulus
GO:0009449 IEA gamma-aminobutyric acid biosynthetic process
GO:0009611 IEA response to wounding
GO:0009986 IEA cell surface
GO:0015813 IEA L-glutamate transport
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016595 IEA glutamate binding
GO:0016597 IEA amino acid binding
GO:0017153 IEA sodium:dicarboxylate symporter activity
GO:0021545 IEA cranial nerve development
GO:0031223 IEA auditory behavior
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0043205 IEA fibril
GO:0046677 IEA response to antibiotic
GO:0048667 IEA cell morphogenesis involved in neuron differentiation
GO:0050806 IEA positive regulation of synaptic transmission
GO:0050885 IEA neuromuscular process controlling balance
GO:0051938 IDA L-glutamate import
GO:0055085 TAS transmembrane transport
GO:0070779 IDA D-aspartate import

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010096 slc1a6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 protein_coding Danio_rerio
ENSMUSG00000005360 Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 protein_coding Mus_musculus

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