C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Eph receptor B3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005958 Ephb3 10090 + 16:21204755-21223305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006112 Ephb3-001 21204755-21223304 protein_coding
  ENSMUST00000159575 Ephb3-003 21216817-21223305 retained_intron
  ENSMUST00000160053 Ephb3-004 21221686-21222687 retained_intron
  ENSMUST00000161063 Ephb3-002 21211095-21222967 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006112ENSMUST00000159575ENSMUST00000160053ENSMUST00000161063
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006112 6.724±4.30 0.834±0.39 9.450±1.17 5.837±2.22 6.674±3.14 16.915±1.69 3.802±0.23 2.360±0.26 0.254±0.19 19.606±0.45 0.177±0.08 5.254±2.24 1.544±0.59 0.254±0.12
ENSMUST00000159575 N/A N/A N/A N/A 0.654±0.00 N/A N/A N/A 0.042±0.01 N/A 0.143±0.10 N/A N/A N/A
ENSMUST00000160053 N/A N/A N/A 3.757±0.00 N/A N/A N/A N/A N/A N/A N/A 1.994±0.00 2.559±0.00 N/A
ENSMUST00000161063 N/A N/A N/A N/A N/A N/A N/A N/A 0.026±0.00 N/A 0.074±0.05 N/A 0.174±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001655 IMP urogenital system development
GO:0005003 ISS ephrin receptor activity
GO:0005005 TAS transmembrane-ephrin receptor activity
GO:0005524 IEA ATP binding
GO:0005887 ISS integral component of plasma membrane
GO:0007411 IMP axon guidance
GO:0007413 IMP axonal fasciculation
GO:0008046 IDA axon guidance receptor activity
GO:0016477 IMP cell migration
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021952 IDA central nervous system projection neuron axonogenesis
GO:0022038 IMP corpus callosum development
GO:0022407 ISS regulation of cell-cell adhesion
GO:0031290 IDA retinal ganglion cell axon guidance
GO:0032314 ISS regulation of Rac GTPase activity
GO:0034446 ISS substrate adhesion-dependent cell spreading
GO:0042995 IEA cell projection
GO:0043088 ISS regulation of Cdc42 GTPase activity
GO:0046777 ISS protein autophosphorylation
GO:0048013 ISS ephrin receptor signaling pathway
GO:0048538 IMP thymus development
GO:0048546 IMP digestive tract morphogenesis
GO:0050770 IDA regulation of axonogenesis
GO:0051965 IMP positive regulation of synapse assembly
GO:0060021 IMP palate development
GO:0060996 IMP dendritic spine development
GO:0060997 IMP dendritic spine morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031548 ephb3a eph receptor B3a protein_coding Danio_rerio
ENSDARG00000033589 EPHB3 (2 of 2) EPH receptor B3 protein_coding Danio_rerio
ENSG00000182580 EPHB3 EPH receptor B3 protein_coding Homo_sapiens

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