C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: four and a half LIM domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008136 Fhl2 10090 - 1:43123074-43196984 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000008280 Fhl2-001 43123074-43163961 protein_coding
  ENSMUST00000185893 Fhl2-002 43123290-43196984 protein_coding
  ENSMUST00000187357 Fhl2-004 43131764-43196761 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000008280ENSMUST00000185893
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000008280 6.334±3.66 13.779±1.22 49.476±11.11 16.758±16.00 3.271±0.64 20.120±2.11 102.889±2.06 15.106±1.02 1.420±1.17 3.101±1.07 2.287±0.93 29.994±9.17 53.934±22.90 1.338±0.62
ENSMUST00000185893 0.516±0.00 N/A N/A N/A 0.543±0.00 N/A 535.037±117.08 5.444±1.24 N/A 2.273±0.56 N/A 8.943±5.90 N/A 4.417±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096O CIL_00096O_0002 VISTA 1:42588323-43189246
CIL_00010E CIL_00010E_0002 CGP 1:43098710-43196984
CIL_00010G CIL_00010G_0002 CGP 1:43123074-43570515

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001649 IEP osteoblast differentiation
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005925 IEA focal adhesion
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0008134 ISS transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0009725 IEA response to hormone
GO:0015629 IEA actin cytoskeleton
GO:0030018 IEA Z disc
GO:0031430 IEA M band
GO:0042802 IEA identical protein binding
GO:0043066 ISS negative regulation of apoptotic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055014 IEP atrial cardiac muscle cell development
GO:0055015 IEP ventricular cardiac muscle cell development
GO:0060347 IEP heart trabecula formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003991 fhl2b four and a half LIM domains 2b protein_coding Danio_rerio
ENSDARG00000042018 fhl2a four and a half LIM domains 2a protein_coding Danio_rerio
ENSG00000115641 FHL2 four and a half LIM domains 2 protein_coding Homo_sapiens

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