C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ELK3, member of ETS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008398 Elk3 10090 - 10:93247414-93311135 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000008542 Elk3-001 93247414-93311135 protein_coding
  ENSMUST00000129827 Elk3-005 93249323-93310811 nonsense_mediated_decay
  ENSMUST00000133365 Elk3-004 93284431-93311135 retained_intron
  ENSMUST00000151153 Elk3-002 93249323-93310969 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000008542ENSMUST00000129827
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000008542 11.916±1.47 14.078±0.89 6.581±0.27 1.967±1.26 11.351±3.39 4.482±0.58 6.751±1.02 6.987±0.56 2.379±0.32 27.329±3.62 1.942±0.39 11.638±3.22 4.163±1.28 0.392±0.20
ENSMUST00000129827 11.270±1.80 19.581±3.56 4.981±0.31 2.770±0.28 14.544±6.85 6.239±1.28 6.560±1.92 6.662±1.41 1.997±0.54 23.601±8.88 1.723±0.48 14.392±6.51 12.405±6.87 0.938±0.37

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005739 IEA mitochondrion
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0030154 IBA cell differentiation
GO:0032422 IEA purine-rich negative regulatory element binding
GO:0042060 IMP wound healing
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018688 elk3 ELK3, ETS-domain protein protein_coding Danio_rerio
ENSG00000111145 ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) protein_coding Homo_sapiens

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