C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ELK3, ETS-domain protein (SRF accessory protein 2)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111145 ELK3 9606 + 12:96194382-96269835 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228741 ELK3-001 96194382-96269835 protein_coding
  ENST00000547249 ELK3-003 96194402-96223682 protein_coding
  ENST00000547860 ELK3-004 96194614-96247211 protein_coding
  ENST00000549529 ELK3-006 96255460-96267490 processed_transcript
  ENST00000549985 ELK3-005 96247131-96267357 nonsense_mediated_decay
  ENST00000552142 ELK3-002 96194545-96267830 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228741
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228741 16.999±0.00 22.156±0.00 1.068±0.54 7.995±4.49 4.459±3.89 3.634±2.66 2.474±0.72 3.017±0.87 10.224±5.80 2.043±0.00 4.764±1.80 6.917±1.57 6.009±2.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AH CIL_0006AH_0002 CGP 12:96000828-96269835
CIL_0001CD CIL_0001CD_0002 CGP 12:96194382-96400560

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEA angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0030154 IBA cell differentiation
GO:0032422 IDA purine-rich negative regulatory element binding
GO:0042060 IEA wound healing
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018688 elk3 ELK3, ETS-domain protein protein_coding Danio_rerio
ENSMUSG00000008398 Elk3 ELK3, member of ETS oncogene family protein_coding Mus_musculus

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