C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor, family C, group 5, member B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008734 Gprc5b 10090 - 7:118972040-118995211 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000008878 Gprc5b-201 118972040-118995211 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryTestisENSMUST00000008878
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Testis
ENSMUST00000008878 28.413±8.76 36.421±14.95 10.462±0.65 17.618±8.97 18.621±5.51 3.776±1.10 7.156±1.23 7.943±1.12 15.288±2.81 6.253±0.37 17.665±4.74 7.133±1.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006MO CIL_0006MO_0002 CGP 7:118842222-118972652
CIL_00008S CIL_00008S_0003 CGP 7:118855760-118995211
CIL_0006MP CIL_0006MP_0002 CGP 7:118972040-119184374

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0004930 IEA G-protein coupled receptor activity
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005886 IDA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007626 IMP locomotory behavior
GO:0009986 IDA cell surface
GO:0010976 IDA positive regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0019901 IDA protein kinase binding
GO:0030295 IEA protein kinase activator activity
GO:0042593 IMP glucose homeostasis
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045121 IDA membrane raft
GO:0045666 IMP positive regulation of neuron differentiation
GO:0045860 IMP positive regulation of protein kinase activity
GO:0050729 IMP positive regulation of inflammatory response
GO:0060907 IMP positive regulation of macrophage cytokine production
GO:0061098 IMP positive regulation of protein tyrosine kinase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075141 gprc5bb G protein-coupled receptor, family C, group 5, member Bb protein_coding Danio_rerio
ENSDARG00000077080 gprc5ba G protein-coupled receptor, family C, group 5, member Ba protein_coding Danio_rerio
ENSG00000167191 GPRC5B G protein-coupled receptor, class C, group 5, member B protein_coding Homo_sapiens

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