C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily M, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000009292 Trpm2 10090 - 10:77907722-77970563 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000105399 Trpm2-003 77962790-77969804 protein_coding
  ENSMUST00000105400 Trpm2-002 77909165-77967457 processed_transcript
  ENSMUST00000105401 Trpm2-001 77907722-77969854 protein_coding
  ENSMUST00000126206 Trpm2-007 77917289-77938037 retained_intron
  ENSMUST00000138238 Trpm2-006 77916058-77920824 retained_intron
  ENSMUST00000140471 Trpm2-005 77909303-77931779 retained_intron
  ENSMUST00000153842 Trpm2-004 77909361-77933031 retained_intron
  ENSMUST00000154996 Trpm2-008 77967045-77970563 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000105400ENSMUST00000105401ENSMUST00000126206ENSMUST00000138238ENSMUST00000140471ENSMUST00000153842
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000105400 0.257±0.16 0.359±0.14 0.134±0.07 1.845±1.53 0.436±0.16 0.231±0.12 0.077±0.03 0.121±0.05 0.733±0.78 0.344±0.11 0.042±0.03 0.214±0.11 0.059±0.03 0.023±0.00
ENSMUST00000105401 N/A 0.255±0.09 0.054±0.02 0.393±0.20 0.264±0.00 N/A 0.036±0.01 0.094±0.03 0.323±0.38 0.094±0.00 N/A 0.136±0.03 N/A 0.017±0.00
ENSMUST00000126206 0.439±0.00 0.574±0.15 N/A 2.270±1.28 0.946±0.43 0.350±0.20 0.108±0.00 0.104±0.03 1.272±1.30 0.323±0.10 N/A 0.330±0.16 0.248±0.00 0.075±0.02
ENSMUST00000138238 0.112±0.00 N/A N/A 0.611±0.00 0.582±0.00 N/A N/A 0.188±0.00 3.147±0.00 N/A 0.049±0.00 0.238±0.00 N/A 0.059±0.00
ENSMUST00000140471 0.110±0.02 0.441±0.00 N/A N/A 0.405±0.21 0.085±0.00 0.037±0.00 N/A 0.354±0.03 0.167±0.00 N/A 0.199±0.04 N/A N/A
ENSMUST00000153842 0.125±0.06 0.269±0.01 0.101±0.00 1.809±1.28 0.395±0.00 0.149±0.06 0.038±0.02 0.090±0.02 0.719±0.46 N/A 0.048±0.02 0.262±0.17 0.358±0.18 0.072±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005261 IEA cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005272 IEA sodium channel activity
GO:0005384 IDA manganese ion transmembrane transporter activity
GO:0005886 IDA plasma membrane
GO:0006828 IDA manganese ion transport
GO:0008152 IEA metabolic process
GO:0016021 IEA integral component of membrane
GO:0033194 IDA response to hydroperoxide
GO:0035725 IEA sodium ion transmembrane transport
GO:0047631 IEA ADP-ribose diphosphatase activity
GO:0070588 IEA calcium ion transmembrane transport
GO:0071421 IDA manganese ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060567 trpm2 transient receptor potential cation channel, subfamily M, member 2 protein_coding Danio_rerio
ENSG00000142185 TRPM2 transient receptor potential cation channel, subfamily M, member 2 protein_coding Homo_sapiens

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