C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily M, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142185 TRPM2 9606 + 21:44350163-44443081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300481 TRPM2-002 44353688-44443081 protein_coding
  ENST00000300482 TRPM2-004 44350163-44443081 protein_coding
  ENST00000397928 TRPM2-001 44353256-44443081 protein_coding
  ENST00000397932 TRPM2-007 44353688-44442358 protein_coding
  ENST00000431901 TRPM2-006 44350304-44366761 protein_coding
  ENST00000490982 TRPM2-003 44425556-44441874 processed_transcript
  ENST00000498430 TRPM2-005 44369121-44443081 processed_transcript
  ENST00000621064 TRPM2-201 44424869-44442644 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300481ENST00000300482ENST00000397932ENST00000431901ENST00000490982ENST00000498430ENST00000621064
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300481 0.055±0.00 N/A N/A 0.501±0.00 N/A N/A 0.199±0.00 N/A N/A N/A N/A N/A N/A
ENST00000300482 N/A N/A 2.283±0.00 0.764±0.00 N/A N/A N/A N/A N/A N/A 0.184±0.00 N/A N/A
ENST00000397932 0.187±0.00 1.175±0.00 1.013±0.00 0.417±0.00 0.117±0.07 0.175±0.06 0.074±0.00 N/A N/A N/A 0.122±0.00 1.257±0.26 N/A
ENST00000431901 N/A N/A N/A N/A 1.172±0.00 0.125±0.00 N/A 1.596±0.00 0.461±0.00 N/A N/A N/A N/A
ENST00000490982 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.068±0.00 N/A N/A
ENST00000498430 0.057±0.00 N/A 0.671±0.25 N/A 0.408±0.00 N/A 0.162±0.00 N/A 0.174±0.00 0.087±0.07 0.318±0.24 0.931±0.16 0.280±0.00
ENST00000621064 0.429±0.00 4.041±0.00 2.731±0.00 1.028±0.00 0.979±0.00 0.397±0.00 1.301±0.00 0.101±0.00 0.741±0.00 0.276±0.00 6.107±4.93 3.183±1.39 1.632±0.65

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005261 IEA cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005272 IEA sodium channel activity
GO:0005384 IEA manganese ion transmembrane transporter activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006816 TAS calcium ion transport
GO:0006828 IEA manganese ion transport
GO:0006979 IEA response to oxidative stress
GO:0008152 IEA metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016787 IEA hydrolase activity
GO:0033194 IEA response to hydroperoxide
GO:0034220 TAS ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0047631 IEA ADP-ribose diphosphatase activity
GO:0055085 TAS:IEA transmembrane transport
GO:0070588 TAS calcium ion transmembrane transport
GO:0071421 IEA manganese ion transmembrane transport
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060567 trpm2 transient receptor potential cation channel, subfamily M, member 2 protein_coding Danio_rerio
ENSMUSG00000009292 Trpm2 transient receptor potential cation channel, subfamily M, member 2 protein_coding Mus_musculus

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