C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium voltage-gated channel, subfamily Q, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000009545 Kcnq1 10090 + 7:143106362-143427042 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000009689 Kcnq1-001 143107254-143427042 protein_coding
  ENSMUST00000185383 Kcnq1-007 143107551-143426125 protein_coding
  ENSMUST00000186284 Kcnq1-004 143108351-143149537 protein_coding
  ENSMUST00000186288 Kcnq1-002 143106515-143149537 protein_coding
  ENSMUST00000186488 Kcnq1-006 143106362-143149537 protein_coding
  ENSMUST00000186798 Kcnq1-003 143106745-143149537 protein_coding
  ENSMUST00000187213 Kcnq1-005 143109194-143149537 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000009689
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000009689 2.662±1.52 6.533±0.37 1.325±0.11 28.350±0.90 16.310±1.73 9.070±3.60 0.437±0.05 10.331±3.25 0.198±0.01 7.208±1.14 1.156±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009BT CIL_0009BT_0002 VISTA 7:142749845-143351046
CIL_0008VI CIL_0008VI_0002 VISTA 7:142812060-143412968
CIL_0008FP CIL_0008FP_0002 VISTA 7:142853813-143455333
CIL_0008A3 CIL_0008A3_0002 VISTA 7:142895498-143499796
CIL_0003FM CIL_0003FM_0003 CGP 7:143106362-143461050

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005249 IEA voltage-gated potassium channel activity
GO:0005251 IBA delayed rectifier potassium channel activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005764 IEA lysosome
GO:0005769 IEA early endosome
GO:0005770 IEA late endosome
GO:0006349 IMP regulation of gene expression by genetic imprinting
GO:0008076 IEA voltage-gated potassium channel complex
GO:0008157 IEA protein phosphatase 1 binding
GO:0016323 IEA basolateral plasma membrane
GO:0016458 IMP gene silencing
GO:0034236 IEA protein kinase A catalytic subunit binding
GO:0034237 IEA protein kinase A regulatory subunit binding
GO:0035690 IEA cellular response to drug
GO:0044325 IEA ion channel binding
GO:0060048 IEA cardiac muscle contraction
GO:0060306 IEA regulation of membrane repolarization
GO:0060307 IEA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060372 IEA regulation of atrial cardiac muscle cell membrane repolarization
GO:0071320 IEA cellular response to cAMP
GO:0071435 IEA potassium ion export
GO:0071805 IEA potassium ion transmembrane transport
GO:0072358 IMP cardiovascular system development
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086008 IEA voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
GO:0086011 IEA membrane repolarization during action potential
GO:0086014 IEA atrial cardiac muscle cell action potential
GO:0086089 IEA voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:0097110 IEA scaffold protein binding
GO:1901381 IEA positive regulation of potassium ion transmembrane transport
GO:1902282 IEA voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059798 kcnq1 potassium voltage-gated channel, KQT-like subfamily, member 1 protein_coding Danio_rerio
ENSG00000053918 KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 protein_coding Homo_sapiens

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