C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014782 Plekhg4 10090 + 8:105373274-105382862 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014927 Plekhg4-001 105375381-105382862 protein_coding
  ENSMUST00000159286 Plekhg4-002 105374904-105382859 nonsense_mediated_decay
  ENSMUST00000160191 Plekhg4-007 105375381-105382241 protein_coding
  ENSMUST00000160650 Plekhg4-004 105373274-105375560 protein_coding
  ENSMUST00000161672 Plekhg4-003 105380494-105382855 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000014927ENSMUST00000159286ENSMUST00000160191ENSMUST00000161672
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000014927 0.191±0.12 0.077±0.00 0.057±0.00 1.775±1.18 0.152±0.06 0.138±0.10 0.052±0.00 N/A 0.023±0.01 0.122±0.00 0.061±0.01 19.712±8.52 0.273±0.19
ENSMUST00000159286 0.095±0.00 0.102±0.00 N/A 0.249±0.00 N/A 0.064±0.00 N/A 0.024±0.00 0.007±0.00 0.037±0.00 0.038±0.00 4.120±1.48 0.060±0.00
ENSMUST00000160191 N/A 0.185±0.10 N/A N/A 0.170±0.09 0.073±0.00 0.032±0.00 0.050±0.01 N/A 0.042±0.00 0.028±0.00 5.123±0.00 0.272±0.00
ENSMUST00000161672 N/A N/A 0.124±0.00 1.297±0.35 0.442±0.00 N/A 0.041±0.00 0.036±0.00 0.037±0.01 N/A 0.067±0.01 12.147±2.51 0.201±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005JZ CIL_0005JZ_0003 CGP 8:105348258-105382862
CIL_00033E CIL_00033E_0002 CGP 8:105373274-105413502

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005575 ND cellular_component
GO:0008150 ND biological_process
GO:0032321 IEA positive regulation of Rho GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038119 si:dkey-65j6.2 pleckstrin homology domain containing, family G (with RhoGef domain) member 4B protein_coding Danio_rerio
ENSDARG00000073684 quo quattro protein_coding Danio_rerio
ENSDARG00000075964 plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 protein_coding Danio_rerio
ENSG00000196155 PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 protein_coding Homo_sapiens

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