C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196155 PLEKHG4 9606 + 16:67277510-67289499 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360461 PLEKHG4-002 67277510-67289479 protein_coding
  ENST00000379344 PLEKHG4-005 67279524-67289473 protein_coding
  ENST00000393966 PLEKHG4-007 67279896-67289055 nonsense_mediated_decay
  ENST00000427155 PLEKHG4-004 67279238-67289479 protein_coding
  ENST00000450733 PLEKHG4-006 67279589-67289499 protein_coding
  ENST00000562144 PLEKHG4-011 67277820-67280273 protein_coding
  ENST00000562289 PLEKHG4-014 67287572-67289307 retained_intron
  ENST00000562744 PLEKHG4-017 67279147-67280934 protein_coding
  ENST00000563969 PLEKHG4-001 67277510-67289479 nonsense_mediated_decay
  ENST00000565773 PLEKHG4-013 67278834-67280368 protein_coding
  ENST00000565899 PLEKHG4-012 67278157-67280265 protein_coding
  ENST00000567136 PLEKHG4-020 67287950-67289072 nonsense_mediated_decay
  ENST00000567938 PLEKHG4-018 67279596-67280275 protein_coding
  ENST00000568621 PLEKHG4-019 67279553-67280152 protein_coding
  ENST00000569875 PLEKHG4-016 67287900-67288942 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360461ENST00000379344ENST00000393966ENST00000427155ENST00000450733ENST00000562289ENST00000563969ENST00000569875
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360461 N/A N/A N/A 0.284±0.00 N/A N/A N/A N/A 0.082±0.00 N/A N/A N/A N/A
ENST00000379344 0.218±0.00 N/A 0.677±0.00 1.110±0.00 N/A 0.125±0.00 0.419±0.00 N/A 0.094±0.00 N/A 1.550±0.41 N/A 18.962±0.00
ENST00000393966 N/A N/A N/A N/A N/A 0.024±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000427155 0.215±0.00 N/A N/A N/A N/A 0.018±0.00 N/A N/A N/A N/A 4.259±2.23 2.240±1.11 7.343±0.00
ENST00000450733 0.305±0.00 0.311±0.00 0.029±0.00 0.709±0.00 0.314±0.00 0.007±0.00 N/A N/A 0.340±0.00 0.076±0.00 1.809±0.58 0.457±0.00 N/A
ENST00000562289 N/A 1.400±0.00 0.421±0.00 N/A 0.535±0.02 0.248±0.00 1.004±0.00 0.274±0.00 0.362±0.00 N/A N/A N/A N/A
ENST00000563969 N/A N/A N/A N/A N/A N/A N/A 0.099±0.00 N/A N/A N/A N/A N/A
ENST00000569875 N/A N/A 0.709±0.00 N/A N/A N/A N/A N/A N/A 1.943±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005JZ CIL_0005JZ_0002 CGP 16:67237683-67289499
CIL_00033E CIL_00033E_0001 CGP 16:67277510-67326763

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000014782 Plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 protein_coding Mus_musculus

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